Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.
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Nature Portfolio
2021
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oai:doaj.org-article:a2974370e88e459b9526094b9f6797a22021-12-02T14:16:13ZSplicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition10.1038/s41467-021-20979-x2041-1723https://doaj.org/article/a2974370e88e459b9526094b9f6797a22021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20979-xhttps://doaj.org/toc/2041-1723Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.E. AgirreA. J. OldfieldN. BelloraA. SegelleR. F. LucoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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DOAJ |
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EN |
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Science Q |
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Science Q E. Agirre A. J. Oldfield N. Bellora A. Segelle R. F. Luco Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| description |
Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines. |
| format |
article |
| author |
E. Agirre A. J. Oldfield N. Bellora A. Segelle R. F. Luco |
| author_facet |
E. Agirre A. J. Oldfield N. Bellora A. Segelle R. F. Luco |
| author_sort |
E. Agirre |
| title |
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| title_short |
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| title_full |
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| title_fullStr |
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| title_full_unstemmed |
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| title_sort |
splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/a2974370e88e459b9526094b9f6797a2 |
| work_keys_str_mv |
AT eagirre splicingassociatedchromatinsignaturesacombinatorialandpositiondependentroleforhistonemarksinsplicingdefinition AT ajoldfield splicingassociatedchromatinsignaturesacombinatorialandpositiondependentroleforhistonemarksinsplicingdefinition AT nbellora splicingassociatedchromatinsignaturesacombinatorialandpositiondependentroleforhistonemarksinsplicingdefinition AT asegelle splicingassociatedchromatinsignaturesacombinatorialandpositiondependentroleforhistonemarksinsplicingdefinition AT rfluco splicingassociatedchromatinsignaturesacombinatorialandpositiondependentroleforhistonemarksinsplicingdefinition |
| _version_ |
1718391742326112256 |