Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition

Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.

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Autores principales:	E. Agirre, A. J. Oldfield, N. Bellora, A. Segelle, R. F. Luco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2974370e88e459b9526094b9f6797a2
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spelling	oai:doaj.org-article:a2974370e88e459b9526094b9f6797a22021-12-02T14:16:13ZSplicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition10.1038/s41467-021-20979-x2041-1723https://doaj.org/article/a2974370e88e459b9526094b9f6797a22021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20979-xhttps://doaj.org/toc/2041-1723Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.E. AgirreA. J. OldfieldN. BelloraA. SegelleR. F. LucoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q E. Agirre A. J. Oldfield N. Bellora A. Segelle R. F. Luco Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
description	Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.
format	article
author	E. Agirre A. J. Oldfield N. Bellora A. Segelle R. F. Luco
author_facet	E. Agirre A. J. Oldfield N. Bellora A. Segelle R. F. Luco
author_sort	E. Agirre
title	Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
title_short	Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
title_full	Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
title_fullStr	Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
title_full_unstemmed	Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
title_sort	splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a2974370e88e459b9526094b9f6797a2
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Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition

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