Invasion of the Central Nervous System by <named-content content-type="genus-species">Cryptococcus neoformans</named-content> Requires a Secreted Fungal Metalloprotease

ABSTRACT Cryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system. Why Cryptococcus neoformans has this remarkable tropism for the CNS is not clear. Recent research on cerebral pathogenesis of C. neoform...

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Autores principales: Kiem Vu, Rick Tham, John P. Uhrig, George R. Thompson, Sarisa Na Pombejra, Mantana Jamklang, Jennifer M. Bautos, Angie Gelli
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/a2978472faeb4b1181847256404fae40
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