Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition

Abstract The characterization of germline genetic variation affecting cancer risk, known as cancer predisposition, is fundamental to preventive and personalized medicine. Studies of genetic cancer predisposition typically identify significant genomic regions based on family-based cohorts or genome-w...

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Bibliographic Details
Main Authors: Nadav Brandes, Nathan Linial, Michal Linial
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
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Online Access:https://doaj.org/article/a29e3e58309f454aa43a5fa62fc78f33
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