Quantifying the Evolutionary Constraints and Potential of Hepatitis C Virus NS5A Protein

ABSTRACT RNA viruses, such as hepatitis C virus (HCV), influenza virus, and SARS-CoV-2, are notorious for their ability to evolve rapidly under selection in novel environments. It is known that the high mutation rate of RNA viruses can generate huge genetic diversity to facilitate viral adaptation....

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Autores principales: Lei Dai, Yushen Du, Hangfei Qi, Christian D. Huber, Dongdong Chen, Tian-Hao Zhang, Nicholas C. Wu, Ergang Wang, James O. Lloyd-Smith, Ren Sun
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
DFE
HCV
Acceso en línea:https://doaj.org/article/a2ace3edb4d846629c7852193d0d3111
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