Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients

Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients

ABSTRACT Cryptococcus neoformans is a pathogenic yeast and a leading cause of life-threatening meningitis in AIDS patients. Natural killer (NK) cells are important immune effector cells that directly recognize and kill C. neoformans via a perforin-dependent cytotoxic mechanism. We previously showed...

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Autores principales: Stephen K. Kyei, Henry Ogbomo, ShuShun Li, Martina Timm-McCann, Richard F. Xiang, Shaunna M. Huston, Anutosh Ganguly, Pina Colarusso, M. John Gill, Christopher H. Mody
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/a2b036e8e6a841d786731795eccab039
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