Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats

Acupuncture has long been used to relieve some inner ear diseases such as deafness and tinnitus. The present study examined the effect of electroacupuncture (EA) on noise-induced hearing loss (NIHL) in animals. A NIHL rat model was established. Electroacupuncture pretreatment at 2 Hz or posttreatmen...

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Autores principales:	Chia-Hao Chang, Chia-Der Lin, Ching-Liang Hsieh
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/a2b8fb04682f4bfca184f5637016e094
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id	oai:doaj.org-article:a2b8fb04682f4bfca184f5637016e094
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spelling	oai:doaj.org-article:a2b8fb04682f4bfca184f5637016e0942021-11-08T02:36:39ZEffect of Electroacupuncture on Noise-Induced Hearing Loss in Rats1741-428810.1155/2021/9114676https://doaj.org/article/a2b8fb04682f4bfca184f5637016e0942021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9114676https://doaj.org/toc/1741-4288Acupuncture has long been used to relieve some inner ear diseases such as deafness and tinnitus. The present study examined the effect of electroacupuncture (EA) on noise-induced hearing loss (NIHL) in animals. A NIHL rat model was established. Electroacupuncture pretreatment at 2 Hz or posttreatment at the right Zhongzhu (TE3) acupoint was applied for 1 hour. Auditory thresholds were measured using auditory brainstem responses (ABRs), and histopathology of the cochlea was examined. The results indicated that the baseline auditory threshold of ABR was not significantly different between the control (no noise), EA-only (only EA without noise), noise (noise exposure only), pre-EA (pretreating EA then noise), and post-EA (noise exposure then posttreating with EA) groups. Significant auditory threshold shifts were found in the noise, pre-EA, and post-EA groups in the immediate period after noise exposure, whereas auditory recovery was better in the pre-EA and post-EA groups than that in the noise group at the three days, one week (W1), two weeks (W2), three weeks (W3), and four weeks(W4) after noise stimulation. Histopathological examination revealed greater loss of the density of spiral ganglion neurons in the noise group than in the control group at W1 and W2. Although significant loss of spiral ganglion loss happened in pre-EA and post-EA groups, such loss was less than the loss of the noise group, especially W1. These results indicate that either pretreatment or posttreatment with EA may facilitate auditory recovery after NIHL. The detailed mechanism through which EA alleviates NIHL requires further study.Chia-Hao ChangChia-Der LinChing-Liang HsiehHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Chia-Hao Chang Chia-Der Lin Ching-Liang Hsieh Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
description	Acupuncture has long been used to relieve some inner ear diseases such as deafness and tinnitus. The present study examined the effect of electroacupuncture (EA) on noise-induced hearing loss (NIHL) in animals. A NIHL rat model was established. Electroacupuncture pretreatment at 2 Hz or posttreatment at the right Zhongzhu (TE3) acupoint was applied for 1 hour. Auditory thresholds were measured using auditory brainstem responses (ABRs), and histopathology of the cochlea was examined. The results indicated that the baseline auditory threshold of ABR was not significantly different between the control (no noise), EA-only (only EA without noise), noise (noise exposure only), pre-EA (pretreating EA then noise), and post-EA (noise exposure then posttreating with EA) groups. Significant auditory threshold shifts were found in the noise, pre-EA, and post-EA groups in the immediate period after noise exposure, whereas auditory recovery was better in the pre-EA and post-EA groups than that in the noise group at the three days, one week (W1), two weeks (W2), three weeks (W3), and four weeks(W4) after noise stimulation. Histopathological examination revealed greater loss of the density of spiral ganglion neurons in the noise group than in the control group at W1 and W2. Although significant loss of spiral ganglion loss happened in pre-EA and post-EA groups, such loss was less than the loss of the noise group, especially W1. These results indicate that either pretreatment or posttreatment with EA may facilitate auditory recovery after NIHL. The detailed mechanism through which EA alleviates NIHL requires further study.
format	article
author	Chia-Hao Chang Chia-Der Lin Ching-Liang Hsieh
author_facet	Chia-Hao Chang Chia-Der Lin Ching-Liang Hsieh
author_sort	Chia-Hao Chang
title	Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
title_short	Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
title_full	Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
title_fullStr	Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
title_full_unstemmed	Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
title_sort	effect of electroacupuncture on noise-induced hearing loss in rats
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/a2b8fb04682f4bfca184f5637016e094
work_keys_str_mv	AT chiahaochang effectofelectroacupunctureonnoiseinducedhearinglossinrats AT chiaderlin effectofelectroacupunctureonnoiseinducedhearinglossinrats AT chinglianghsieh effectofelectroacupunctureonnoiseinducedhearinglossinrats
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Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats

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