Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent

Abstract The central circadian pacemaker (Suprachiasmatic Nuclei, SCN) maintains the phase relationship with the external world thanks to the light/dark cycle. Light intensity, spectra, and timing are important for SCN synchronisation. Exposure to blue-light at night leads to circadian misalignment...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Maria Angeles Bonmati-Carrion, Beatriz Baño-Otalora, Juan Antonio Madrid, Maria Angeles Rol
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a2baf82909ef45b2b16fb9a668e15d6c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a2baf82909ef45b2b16fb9a668e15d6c
record_format	dspace
spelling	oai:doaj.org-article:a2baf82909ef45b2b16fb9a668e15d6c2021-12-02T15:05:51ZLight color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent10.1038/s41598-017-08691-72045-2322https://doaj.org/article/a2baf82909ef45b2b16fb9a668e15d6c2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08691-7https://doaj.org/toc/2045-2322Abstract The central circadian pacemaker (Suprachiasmatic Nuclei, SCN) maintains the phase relationship with the external world thanks to the light/dark cycle. Light intensity, spectra, and timing are important for SCN synchronisation. Exposure to blue-light at night leads to circadian misalignment that could be avoided by using less circadian-disruptive wavelengths. This study tests the capacity of a diurnal Octodon degus and nocturnal Rattus norvegicus to synchronise to different nocturnal lights. Animals were subjected to combined red-green-blue lights (RGB) during the day and to: darkness; red light (R); combined red-green LED (RG) lights; and combined red-green-violet LED (RGV) lights during the night. Activity rhythms free-ran in rats under a RGB:RG cycle and became arrhythmic under RGB:RGV. Degus remained synchronised, despite the fact that day and night-time lighting systems differed only in spectra, but not in intensity. For degus SCN c-Fos activation by light was stronger with RGB-light than with RGV. This could be relevant for developing lighting that reduces the disruptive effects of nocturnal light in humans, without compromising chromaticity.Maria Angeles Bonmati-CarrionBeatriz Baño-OtaloraJuan Antonio MadridMaria Angeles RolNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Maria Angeles Bonmati-Carrion Beatriz Baño-Otalora Juan Antonio Madrid Maria Angeles Rol Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent
description	Abstract The central circadian pacemaker (Suprachiasmatic Nuclei, SCN) maintains the phase relationship with the external world thanks to the light/dark cycle. Light intensity, spectra, and timing are important for SCN synchronisation. Exposure to blue-light at night leads to circadian misalignment that could be avoided by using less circadian-disruptive wavelengths. This study tests the capacity of a diurnal Octodon degus and nocturnal Rattus norvegicus to synchronise to different nocturnal lights. Animals were subjected to combined red-green-blue lights (RGB) during the day and to: darkness; red light (R); combined red-green LED (RG) lights; and combined red-green-violet LED (RGV) lights during the night. Activity rhythms free-ran in rats under a RGB:RG cycle and became arrhythmic under RGB:RGV. Degus remained synchronised, despite the fact that day and night-time lighting systems differed only in spectra, but not in intensity. For degus SCN c-Fos activation by light was stronger with RGB-light than with RGV. This could be relevant for developing lighting that reduces the disruptive effects of nocturnal light in humans, without compromising chromaticity.
format	article
author	Maria Angeles Bonmati-Carrion Beatriz Baño-Otalora Juan Antonio Madrid Maria Angeles Rol
author_facet	Maria Angeles Bonmati-Carrion Beatriz Baño-Otalora Juan Antonio Madrid Maria Angeles Rol
author_sort	Maria Angeles Bonmati-Carrion
title	Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent
title_short	Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent
title_full	Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent
title_fullStr	Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent
title_full_unstemmed	Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent
title_sort	light color importance for circadian entrainment in a diurnal (octodon degus) and a nocturnal (rattus norvegicus) rodent
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a2baf82909ef45b2b16fb9a668e15d6c
work_keys_str_mv	AT mariaangelesbonmaticarrion lightcolorimportanceforcircadianentrainmentinadiurnaloctodondegusandanocturnalrattusnorvegicusrodent AT beatrizbanootalora lightcolorimportanceforcircadianentrainmentinadiurnaloctodondegusandanocturnalrattusnorvegicusrodent AT juanantoniomadrid lightcolorimportanceforcircadianentrainmentinadiurnaloctodondegusandanocturnalrattusnorvegicusrodent AT mariaangelesrol lightcolorimportanceforcircadianentrainmentinadiurnaloctodondegusandanocturnalrattusnorvegicusrodent
_version_	1718388662523133952

Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent

Ejemplares similares