Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications.

Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications.

Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem cells, normal hematopoietic cells and different...

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Auteurs principaux: Maria Carmela Vegliante, Cristina Royo, Jara Palomero, Itziar Salaverria, Balazs Balint, Idoia Martín-Guerrero, Xabier Agirre, Amaia Lujambio, Julia Richter, Silvia Xargay-Torrent, Silvia Bea, Luis Hernandez, Anna Enjuanes, María José Calasanz, Andreas Rosenwald, German Ott, José Roman-Gomez, Felipe Prosper, Manel Esteller, Pedro Jares, Reiner Siebert, Elias Campo, José I Martín-Subero, Virginia Amador
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/a2c641b7ae244f298e229b4d1dca17bd
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