An analytical theory of balanced cellular growth

Genome-scale models of microbial metabolism largely ignore reaction kinetics. Here, the authors develop a general mathematical framework for modeling cellular growth with explicit non-linear reaction kinetics and use it to glean insights into the principles of cellular resource allocation and growth...

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Detalles Bibliográficos
Autores principales:	Hugo Dourado, Martin J. Lercher
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2c6498bcef043a6befe71c2f267545f
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spelling	oai:doaj.org-article:a2c6498bcef043a6befe71c2f267545f2021-12-02T16:56:48ZAn analytical theory of balanced cellular growth10.1038/s41467-020-14751-w2041-1723https://doaj.org/article/a2c6498bcef043a6befe71c2f267545f2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14751-whttps://doaj.org/toc/2041-1723Genome-scale models of microbial metabolism largely ignore reaction kinetics. Here, the authors develop a general mathematical framework for modeling cellular growth with explicit non-linear reaction kinetics and use it to glean insights into the principles of cellular resource allocation and growth.Hugo DouradoMartin J. LercherNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hugo Dourado Martin J. Lercher An analytical theory of balanced cellular growth
description	Genome-scale models of microbial metabolism largely ignore reaction kinetics. Here, the authors develop a general mathematical framework for modeling cellular growth with explicit non-linear reaction kinetics and use it to glean insights into the principles of cellular resource allocation and growth.
format	article
author	Hugo Dourado Martin J. Lercher
author_facet	Hugo Dourado Martin J. Lercher
author_sort	Hugo Dourado
title	An analytical theory of balanced cellular growth
title_short	An analytical theory of balanced cellular growth
title_full	An analytical theory of balanced cellular growth
title_fullStr	An analytical theory of balanced cellular growth
title_full_unstemmed	An analytical theory of balanced cellular growth
title_sort	analytical theory of balanced cellular growth
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a2c6498bcef043a6befe71c2f267545f
work_keys_str_mv	AT hugodourado ananalyticaltheoryofbalancedcellulargrowth AT martinjlercher ananalyticaltheoryofbalancedcellulargrowth AT hugodourado analyticaltheoryofbalancedcellulargrowth AT martinjlercher analyticaltheoryofbalancedcellulargrowth
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An analytical theory of balanced cellular growth

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