Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association

Fungal infections occurring in immunocompromised patients after immuno-chemotherapy treatment, are often difficult to eradicate and capable of even being fatal. Systemic mycoses affecting severely immunocompromised patients often manifest acutely with rapidly progressive pneumonia, fungemia, or man...

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Autores principales: Andrea Duminuco, Elisa Mauro, Giuseppe A. M. Palumbo, Bruno Garibaldi, Marina Parisi, Francesco Di Raimondo, Cinzia Maugeri, Calogero Vetro
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Publicado: PAGEPress Publications 2021
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Acceso en línea:https://doaj.org/article/a2c92240702f4e08a388d4bac8cdc68f
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spelling oai:doaj.org-article:a2c92240702f4e08a388d4bac8cdc68f2021-11-26T14:38:44ZTherapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association10.4081/hr.2021.93292038-83222038-8330https://doaj.org/article/a2c92240702f4e08a388d4bac8cdc68f2021-11-01T00:00:00Zhttps://www.pagepress.org/journals/index.php/hr/article/view/9329https://doaj.org/toc/2038-8322https://doaj.org/toc/2038-8330 Fungal infections occurring in immunocompromised patients after immuno-chemotherapy treatment, are often difficult to eradicate and capable of even being fatal. Systemic mycoses affecting severely immunocompromised patients often manifest acutely with rapidly progressive pneumonia, fungemia, or manifestations of extrapulmonary dissemination. Opportunistic fungal infections (mycoses) include several pathogens elements, as Candidiasis, Aspergillosis, Mucormycosis (zygomycosis) and Fusariosis. Prompt diagnosis and effective therapy are needed to improve the associated morbidity and mortality, especially in cases with non-canonical fungal localizations and not responsive to the available antifungal drugs. Andrea DuminucoElisa MauroGiuseppe A. M. PalumboBruno GaribaldiMarina ParisiFrancesco Di RaimondoCinzia MaugeriCalogero VetroPAGEPress PublicationsarticleFungal infectionCandidaisavuconazolecaspofungincombined antifungal therapyhematological patientsDiseases of the blood and blood-forming organsRC633-647.5ENHematology Reports, Vol 13, Iss 4 (2021)
institution DOAJ
collection DOAJ
language EN
topic Fungal infection
Candida
isavuconazole
caspofungin
combined antifungal therapy
hematological patients
Diseases of the blood and blood-forming organs
RC633-647.5
spellingShingle Fungal infection
Candida
isavuconazole
caspofungin
combined antifungal therapy
hematological patients
Diseases of the blood and blood-forming organs
RC633-647.5
Andrea Duminuco
Elisa Mauro
Giuseppe A. M. Palumbo
Bruno Garibaldi
Marina Parisi
Francesco Di Raimondo
Cinzia Maugeri
Calogero Vetro
Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
description Fungal infections occurring in immunocompromised patients after immuno-chemotherapy treatment, are often difficult to eradicate and capable of even being fatal. Systemic mycoses affecting severely immunocompromised patients often manifest acutely with rapidly progressive pneumonia, fungemia, or manifestations of extrapulmonary dissemination. Opportunistic fungal infections (mycoses) include several pathogens elements, as Candidiasis, Aspergillosis, Mucormycosis (zygomycosis) and Fusariosis. Prompt diagnosis and effective therapy are needed to improve the associated morbidity and mortality, especially in cases with non-canonical fungal localizations and not responsive to the available antifungal drugs.
format article
author Andrea Duminuco
Elisa Mauro
Giuseppe A. M. Palumbo
Bruno Garibaldi
Marina Parisi
Francesco Di Raimondo
Cinzia Maugeri
Calogero Vetro
author_facet Andrea Duminuco
Elisa Mauro
Giuseppe A. M. Palumbo
Bruno Garibaldi
Marina Parisi
Francesco Di Raimondo
Cinzia Maugeri
Calogero Vetro
author_sort Andrea Duminuco
title Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
title_short Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
title_full Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
title_fullStr Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
title_full_unstemmed Therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
title_sort therapeutic innovation for multi-resistant candidemics: synergy of isavuconazole and caspofungin association
publisher PAGEPress Publications
publishDate 2021
url https://doaj.org/article/a2c92240702f4e08a388d4bac8cdc68f
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