Introns control stochastic allele expression bias

Stochastic autosomal allele expression bias has been widely documented, yet the mechanisms behind this consequential phenomenon remain poorly understood. Here the authors show that the presence of introns greatly restricts monoallelic expression in a C. elegans model.

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Autores principales:	Bryan Sands, Soo Yun, Alexander R. Mendenhall
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2d43299d8b047f0bcea8e2526b1ee70
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spelling	oai:doaj.org-article:a2d43299d8b047f0bcea8e2526b1ee702021-11-14T12:35:49ZIntrons control stochastic allele expression bias10.1038/s41467-021-26798-42041-1723https://doaj.org/article/a2d43299d8b047f0bcea8e2526b1ee702021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26798-4https://doaj.org/toc/2041-1723Stochastic autosomal allele expression bias has been widely documented, yet the mechanisms behind this consequential phenomenon remain poorly understood. Here the authors show that the presence of introns greatly restricts monoallelic expression in a C. elegans model.Bryan SandsSoo YunAlexander R. MendenhallNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bryan Sands Soo Yun Alexander R. Mendenhall Introns control stochastic allele expression bias
description	Stochastic autosomal allele expression bias has been widely documented, yet the mechanisms behind this consequential phenomenon remain poorly understood. Here the authors show that the presence of introns greatly restricts monoallelic expression in a C. elegans model.
format	article
author	Bryan Sands Soo Yun Alexander R. Mendenhall
author_facet	Bryan Sands Soo Yun Alexander R. Mendenhall
author_sort	Bryan Sands
title	Introns control stochastic allele expression bias
title_short	Introns control stochastic allele expression bias
title_full	Introns control stochastic allele expression bias
title_fullStr	Introns control stochastic allele expression bias
title_full_unstemmed	Introns control stochastic allele expression bias
title_sort	introns control stochastic allele expression bias
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a2d43299d8b047f0bcea8e2526b1ee70
work_keys_str_mv	AT bryansands intronscontrolstochasticalleleexpressionbias AT sooyun intronscontrolstochasticalleleexpressionbias AT alexanderrmendenhall intronscontrolstochasticalleleexpressionbias
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Introns control stochastic allele expression bias

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