COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS

Objective: To determine and compare serum ferritin levels in non-alcoholic fatty liver disease (NAFLD) patients of our ethnicity. Study Design: Cross sectional comparative study. Place and Duration of Study: The study was conducted at Radiology department of Shalamar Hospital, Medical OPD of C...

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Autores principales: Mehwish Qamar, Syeda Abeer Fatima, Haseeb Ahmed Khan, Qudsia Umaira Khan, Amna Nadeem, Hina Sikandar
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2020
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Acceso en línea:https://doaj.org/article/a2dfad8dd08441529e91d6860690ce73
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spelling oai:doaj.org-article:a2dfad8dd08441529e91d6860690ce732021-12-02T19:18:23ZCOMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS0030-96482411-8842https://doaj.org/article/a2dfad8dd08441529e91d6860690ce732020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5873https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine and compare serum ferritin levels in non-alcoholic fatty liver disease (NAFLD) patients of our ethnicity. Study Design: Cross sectional comparative study. Place and Duration of Study: The study was conducted at Radiology department of Shalamar Hospital, Medical OPD of Combined Military Hospital, Lahore and Medical OPD of Omer Hospital, Lahore, from Jul 2015 to Sep 2015. Methodology: A total number of 43 non-alcoholic fatty liver disease patients diagnosed after ultrasonography were included in the study. An equal number of age, gender and body mass index (BMI) matched healthy controls were selected by non-probability purposive sampling. Fasting serum ferritin levels, body mass index and waist circumference were measured in both the cases and controls. Data were entered and analyzed on SPSS 21. For quantitative data median IQR was calculated. Mann Whitney U-test was used for group comparison. To find an association, Spearman‟s Ranked correlation was applied. A p-value of ≤0.05 was taken as significant. Results: The non-alcoholic fatty liver disease cases had significantly higher serum ferritin (p<0.001) compared to the controls and a significant correlation between ferritin with body mass index and waist circumference in the non-alcoholic fatty liver disease subjects was recorded (p=0.04 and p=0.03 respectively). Conclusion: The non-alcoholic fatty liver disease patients have higher levels of serum ferritin as compared to the healthy controls in our ethnicity but within normal range.Mehwish QamarSyeda Abeer FatimaHaseeb Ahmed KhanQudsia Umaira KhanAmna NadeemHina SikandarArmy Medical College Rawalpindiarticlebminafldserum ferritinwaist circumferenceMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 6, Pp 1782-1786 (2020)
institution DOAJ
collection DOAJ
language EN
topic bmi
nafld
serum ferritin
waist circumference
Medicine
R
Medicine (General)
R5-920
spellingShingle bmi
nafld
serum ferritin
waist circumference
Medicine
R
Medicine (General)
R5-920
Mehwish Qamar
Syeda Abeer Fatima
Haseeb Ahmed Khan
Qudsia Umaira Khan
Amna Nadeem
Hina Sikandar
COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS
description Objective: To determine and compare serum ferritin levels in non-alcoholic fatty liver disease (NAFLD) patients of our ethnicity. Study Design: Cross sectional comparative study. Place and Duration of Study: The study was conducted at Radiology department of Shalamar Hospital, Medical OPD of Combined Military Hospital, Lahore and Medical OPD of Omer Hospital, Lahore, from Jul 2015 to Sep 2015. Methodology: A total number of 43 non-alcoholic fatty liver disease patients diagnosed after ultrasonography were included in the study. An equal number of age, gender and body mass index (BMI) matched healthy controls were selected by non-probability purposive sampling. Fasting serum ferritin levels, body mass index and waist circumference were measured in both the cases and controls. Data were entered and analyzed on SPSS 21. For quantitative data median IQR was calculated. Mann Whitney U-test was used for group comparison. To find an association, Spearman‟s Ranked correlation was applied. A p-value of ≤0.05 was taken as significant. Results: The non-alcoholic fatty liver disease cases had significantly higher serum ferritin (p<0.001) compared to the controls and a significant correlation between ferritin with body mass index and waist circumference in the non-alcoholic fatty liver disease subjects was recorded (p=0.04 and p=0.03 respectively). Conclusion: The non-alcoholic fatty liver disease patients have higher levels of serum ferritin as compared to the healthy controls in our ethnicity but within normal range.
format article
author Mehwish Qamar
Syeda Abeer Fatima
Haseeb Ahmed Khan
Qudsia Umaira Khan
Amna Nadeem
Hina Sikandar
author_facet Mehwish Qamar
Syeda Abeer Fatima
Haseeb Ahmed Khan
Qudsia Umaira Khan
Amna Nadeem
Hina Sikandar
author_sort Mehwish Qamar
title COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS
title_short COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS
title_full COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS
title_fullStr COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS
title_full_unstemmed COMPARISON OF SERUM FERRITIN LEVELS IN NAFLD PATIENTS AND HEALTHY CONTROLS
title_sort comparison of serum ferritin levels in nafld patients and healthy controls
publisher Army Medical College Rawalpindi
publishDate 2020
url https://doaj.org/article/a2dfad8dd08441529e91d6860690ce73
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