An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India

BACKGROUND: Significant blood loss and requirement of allogenic blood transfusion during or after total knee replacement (TKR) have been reported. Incidence of blood transfusion in TKR is highly variable and depends on several factors. We investigated the blood utilization in patients undergoing TKR...

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Autores principales: Sudipta Sekhar Das, Ranjan Kamilya, Rathindra Nath Biswas, Susanta Ghosh
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Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2021
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Acceso en línea:https://doaj.org/article/a2e1aa9dc6204d978e24f3d73ec9c819
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spelling oai:doaj.org-article:a2e1aa9dc6204d978e24f3d73ec9c8192021-11-12T10:08:28ZAn insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India0973-62471998-356510.4103/ajts.ajts_186_20https://doaj.org/article/a2e1aa9dc6204d978e24f3d73ec9c8192021-01-01T00:00:00Zhttp://www.ajts.org/article.asp?issn=0973-6247;year=2021;volume=15;issue=2;spage=133;epage=139;aulast=Dashttps://doaj.org/toc/0973-6247https://doaj.org/toc/1998-3565BACKGROUND: Significant blood loss and requirement of allogenic blood transfusion during or after total knee replacement (TKR) have been reported. Incidence of blood transfusion in TKR is highly variable and depends on several factors. We investigated the blood utilization in patients undergoing TKR in our hospital and depicted the important risk factors that determine the need of allogenic blood transfusion in primary unilateral TKR.MATERIALS AND METHODS: The study included 1241 consecutive patients undergoing primary unilateral total knee arthroplasty. All the surgeries were performed by a single surgical team of orthopedists following standard procedure. Patient and disease details were obtained from patient file and hospital information system. Compatibility test was performed in blood bank before blood reservation following mandatory guidelines. Details of test, blood issue, and blood transfusion were documented in the blood bank.RESULTS: Of 1241 enrolled patients, 1069 (86.2%) were female. The median age of patients was 66 years with mean preoperative hemoglobin of 9.9 g/dL. Allogenic blood transfused was needed in 223 (17.9%) patients. Diabetes mellitus, hypertension, thyroid disorders, and chronic heart diseases were the major comorbid conditions. Risk factors such as gender, American Society of Anesthesiologists score, preoperative hemoglobin, and intraoperative and postoperative blood losses were significantly associated with blood transfusion.CONCLUSION: The risk factors determining blood transfusion in TKR vary between studies, however, all centers should establish standard operating procedures describing the surgical procedure and transfusion support in TKR. In addition, each center may develop specific blood management strategy to rationalize blood transfusion in TKR and overall successful care in TKR.Sudipta Sekhar DasRanjan KamilyaRathindra Nath BiswasSusanta GhoshWolters Kluwer Medknow Publicationsarticleallogenic blood transfusionosteoarthritispreoperative hemoglobintotal knee arthroplastytotal knee replacementDiseases of the blood and blood-forming organsRC633-647.5ENAsian Journal of Transfusion Science, Vol 15, Iss 2, Pp 133-139 (2021)
institution DOAJ
collection DOAJ
language EN
topic allogenic blood transfusion
osteoarthritis
preoperative hemoglobin
total knee arthroplasty
total knee replacement
Diseases of the blood and blood-forming organs
RC633-647.5
spellingShingle allogenic blood transfusion
osteoarthritis
preoperative hemoglobin
total knee arthroplasty
total knee replacement
Diseases of the blood and blood-forming organs
RC633-647.5
Sudipta Sekhar Das
Ranjan Kamilya
Rathindra Nath Biswas
Susanta Ghosh
An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India
description BACKGROUND: Significant blood loss and requirement of allogenic blood transfusion during or after total knee replacement (TKR) have been reported. Incidence of blood transfusion in TKR is highly variable and depends on several factors. We investigated the blood utilization in patients undergoing TKR in our hospital and depicted the important risk factors that determine the need of allogenic blood transfusion in primary unilateral TKR.MATERIALS AND METHODS: The study included 1241 consecutive patients undergoing primary unilateral total knee arthroplasty. All the surgeries were performed by a single surgical team of orthopedists following standard procedure. Patient and disease details were obtained from patient file and hospital information system. Compatibility test was performed in blood bank before blood reservation following mandatory guidelines. Details of test, blood issue, and blood transfusion were documented in the blood bank.RESULTS: Of 1241 enrolled patients, 1069 (86.2%) were female. The median age of patients was 66 years with mean preoperative hemoglobin of 9.9 g/dL. Allogenic blood transfused was needed in 223 (17.9%) patients. Diabetes mellitus, hypertension, thyroid disorders, and chronic heart diseases were the major comorbid conditions. Risk factors such as gender, American Society of Anesthesiologists score, preoperative hemoglobin, and intraoperative and postoperative blood losses were significantly associated with blood transfusion.CONCLUSION: The risk factors determining blood transfusion in TKR vary between studies, however, all centers should establish standard operating procedures describing the surgical procedure and transfusion support in TKR. In addition, each center may develop specific blood management strategy to rationalize blood transfusion in TKR and overall successful care in TKR.
format article
author Sudipta Sekhar Das
Ranjan Kamilya
Rathindra Nath Biswas
Susanta Ghosh
author_facet Sudipta Sekhar Das
Ranjan Kamilya
Rathindra Nath Biswas
Susanta Ghosh
author_sort Sudipta Sekhar Das
title An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India
title_short An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India
title_full An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India
title_fullStr An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India
title_full_unstemmed An insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in Eastern India
title_sort insight into the utilization of allogenic blood transfusion and factors affecting blood transfusion in total knee replacement surgery in a tertiary care hospital in eastern india
publisher Wolters Kluwer Medknow Publications
publishDate 2021
url https://doaj.org/article/a2e1aa9dc6204d978e24f3d73ec9c819
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