Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion

Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.

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Autores principales:	Julia A. Horstmann, Michele Lunelli, Hélène Cazzola, Johannes Heidemann, Caroline Kühne, Pascal Steffen, Sandra Szefs, Claire Rossi, Ravi K. Lokareddy, Chu Wang, Laurine Lemaire, Kelly T. Hughes, Charlotte Uetrecht, Hartmut Schlüter, Guntram A. Grassl, Theresia E. B. Stradal, Yannick Rossez, Michael Kolbe, Marc Erhardt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2e29bfad3e243b1b5b15ef5ca3af75a
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spelling	oai:doaj.org-article:a2e29bfad3e243b1b5b15ef5ca3af75a2021-12-02T15:37:11ZMethylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion10.1038/s41467-020-15738-32041-1723https://doaj.org/article/a2e29bfad3e243b1b5b15ef5ca3af75a2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15738-3https://doaj.org/toc/2041-1723Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.Julia A. HorstmannMichele LunelliHélène CazzolaJohannes HeidemannCaroline KühnePascal SteffenSandra SzefsClaire RossiRavi K. LokareddyChu WangLaurine LemaireKelly T. HughesCharlotte UetrechtHartmut SchlüterGuntram A. GrasslTheresia E. B. StradalYannick RossezMichael KolbeMarc ErhardtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julia A. Horstmann Michele Lunelli Hélène Cazzola Johannes Heidemann Caroline Kühne Pascal Steffen Sandra Szefs Claire Rossi Ravi K. Lokareddy Chu Wang Laurine Lemaire Kelly T. Hughes Charlotte Uetrecht Hartmut Schlüter Guntram A. Grassl Theresia E. B. Stradal Yannick Rossez Michael Kolbe Marc Erhardt Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
description	Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.
format	article
author	Julia A. Horstmann Michele Lunelli Hélène Cazzola Johannes Heidemann Caroline Kühne Pascal Steffen Sandra Szefs Claire Rossi Ravi K. Lokareddy Chu Wang Laurine Lemaire Kelly T. Hughes Charlotte Uetrecht Hartmut Schlüter Guntram A. Grassl Theresia E. B. Stradal Yannick Rossez Michael Kolbe Marc Erhardt
author_facet	Julia A. Horstmann Michele Lunelli Hélène Cazzola Johannes Heidemann Caroline Kühne Pascal Steffen Sandra Szefs Claire Rossi Ravi K. Lokareddy Chu Wang Laurine Lemaire Kelly T. Hughes Charlotte Uetrecht Hartmut Schlüter Guntram A. Grassl Theresia E. B. Stradal Yannick Rossez Michael Kolbe Marc Erhardt
author_sort	Julia A. Horstmann
title	Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
title_short	Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
title_full	Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
title_fullStr	Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
title_full_unstemmed	Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
title_sort	methylation of salmonella typhimurium flagella promotes bacterial adhesion and host cell invasion
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a2e29bfad3e243b1b5b15ef5ca3af75a
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Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion

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