PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA

This aim of the study was to research the prevalence of genotypes and alleles of2756A>G polymorphism of gene of methionine synthase (MTR) gene in Russian and Buryat populations of Eastern Siberia. We used DNA blood database of children and teenagers of the Russian and Buryat nationality living in...

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Autores principales:	K. D. Ievleva, T. A. Bairova, S. I. Kolesnikov, O. V. Kalyuzhnaya
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2014
Materias:	homocysteine methionine synthase (mtr) multifactorial pathology 2756a>g polymorphism folate cycle Science Q
Acceso en línea:	https://doaj.org/article/a2ec2041d0bb496387d7021d187353e9
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spelling	oai:doaj.org-article:a2ec2041d0bb496387d7021d187353e92021-11-23T06:14:31ZPREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA2541-94202587-9596https://doaj.org/article/a2ec2041d0bb496387d7021d187353e92014-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1848https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596This aim of the study was to research the prevalence of genotypes and alleles of2756A>G polymorphism of gene of methionine synthase (MTR) gene in Russian and Buryat populations of Eastern Siberia. We used DNA blood database of children and teenagers of the Russian and Buryat nationality living in Eastern Siberia. Genotyping was carried out using standard PCR method. Prevalence of minor G-allele in Russian population was 25,7 %, in Buryat population - 13,2 %. We revealed differences in prevalence of genotypes and alleles between studied groups (p = 0,051; p = 0,032).K. D. IevlevaT. A. BairovaS. I. KolesnikovO. V. KalyuzhnayaScientific Сentre for Family Health and Human Reproduction Problemsarticlehomocysteinemethionine synthase (mtr)multifactorial pathology2756a>g polymorphismfolate cycleScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 108-110 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	homocysteine methionine synthase (mtr) multifactorial pathology 2756a>g polymorphism folate cycle Science Q
spellingShingle	homocysteine methionine synthase (mtr) multifactorial pathology 2756a>g polymorphism folate cycle Science Q K. D. Ievleva T. A. Bairova S. I. Kolesnikov O. V. Kalyuzhnaya PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA
description	This aim of the study was to research the prevalence of genotypes and alleles of2756A>G polymorphism of gene of methionine synthase (MTR) gene in Russian and Buryat populations of Eastern Siberia. We used DNA blood database of children and teenagers of the Russian and Buryat nationality living in Eastern Siberia. Genotyping was carried out using standard PCR method. Prevalence of minor G-allele in Russian population was 25,7 %, in Buryat population - 13,2 %. We revealed differences in prevalence of genotypes and alleles between studied groups (p = 0,051; p = 0,032).
format	article
author	K. D. Ievleva T. A. Bairova S. I. Kolesnikov O. V. Kalyuzhnaya
author_facet	K. D. Ievleva T. A. Bairova S. I. Kolesnikov O. V. Kalyuzhnaya
author_sort	K. D. Ievleva
title	PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA
title_short	PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA
title_full	PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA
title_fullStr	PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA
title_full_unstemmed	PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA
title_sort	prevalence of 2756a>g polymorphism of methionine synthase gene in populations of eastern siberia
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2014
url	https://doaj.org/article/a2ec2041d0bb496387d7021d187353e9
work_keys_str_mv	AT kdievleva prevalenceof2756agpolymorphismofmethioninesynthasegeneinpopulationsofeasternsiberia AT tabairova prevalenceof2756agpolymorphismofmethioninesynthasegeneinpopulationsofeasternsiberia AT sikolesnikov prevalenceof2756agpolymorphismofmethioninesynthasegeneinpopulationsofeasternsiberia AT ovkalyuzhnaya prevalenceof2756agpolymorphismofmethioninesynthasegeneinpopulationsofeasternsiberia
_version_	1718417087505891328

PREVALENCE OF 2756A>G POLYMORPHISM OF METHIONINE SYNTHASE GENE IN POPULATIONS OF EASTERN SIBERIA

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