Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor

The hypoxic microenvironment in solid tumors limits the efficacy of photodynamic therapy (PDT) since oxygen is necessary to produce high cytotoxic singlet oxygen species. Here, the authors develop an improved self-assembled single-atom nanozyme which allows oxygen generation to enhance PDT efficacy.

Guardado en:

Detalles Bibliográficos
Autores principales:	Dongdong Wang, Huihui Wu, Soo Zeng Fiona Phua, Guangbao Yang, Wei Qi Lim, Long Gu, Cheng Qian, Haibao Wang, Zhen Guo, Hongzhong Chen, Yanli Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2ef257ac4894317964ca7d79d63039f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a2ef257ac4894317964ca7d79d63039f
record_format	dspace
spelling	oai:doaj.org-article:a2ef257ac4894317964ca7d79d63039f2021-12-02T14:41:03ZSelf-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor10.1038/s41467-019-14199-72041-1723https://doaj.org/article/a2ef257ac4894317964ca7d79d63039f2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14199-7https://doaj.org/toc/2041-1723The hypoxic microenvironment in solid tumors limits the efficacy of photodynamic therapy (PDT) since oxygen is necessary to produce high cytotoxic singlet oxygen species. Here, the authors develop an improved self-assembled single-atom nanozyme which allows oxygen generation to enhance PDT efficacy.Dongdong WangHuihui WuSoo Zeng Fiona PhuaGuangbao YangWei Qi LimLong GuCheng QianHaibao WangZhen GuoHongzhong ChenYanli ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dongdong Wang Huihui Wu Soo Zeng Fiona Phua Guangbao Yang Wei Qi Lim Long Gu Cheng Qian Haibao Wang Zhen Guo Hongzhong Chen Yanli Zhao Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
description	The hypoxic microenvironment in solid tumors limits the efficacy of photodynamic therapy (PDT) since oxygen is necessary to produce high cytotoxic singlet oxygen species. Here, the authors develop an improved self-assembled single-atom nanozyme which allows oxygen generation to enhance PDT efficacy.
format	article
author	Dongdong Wang Huihui Wu Soo Zeng Fiona Phua Guangbao Yang Wei Qi Lim Long Gu Cheng Qian Haibao Wang Zhen Guo Hongzhong Chen Yanli Zhao
author_facet	Dongdong Wang Huihui Wu Soo Zeng Fiona Phua Guangbao Yang Wei Qi Lim Long Gu Cheng Qian Haibao Wang Zhen Guo Hongzhong Chen Yanli Zhao
author_sort	Dongdong Wang
title	Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
title_short	Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
title_full	Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
title_fullStr	Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
title_full_unstemmed	Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
title_sort	self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a2ef257ac4894317964ca7d79d63039f
work_keys_str_mv	AT dongdongwang selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT huihuiwu selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT soozengfionaphua selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT guangbaoyang selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT weiqilim selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT longgu selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT chengqian selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT haibaowang selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT zhenguo selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT hongzhongchen selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor AT yanlizhao selfassembledsingleatomnanozymeforenhancedphotodynamictherapytreatmentoftumor
_version_	1718390071385653248

Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor

Ejemplares similares