Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

Background: SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. Methods: We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model...

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Autores principales:	Courtney Tindle, MacKenzie Fuller, Ayden Fonseca, Sahar Taheri, Stella-Rita Ibeawuchi, Nathan Beutler, Gajanan Dattatray Katkar, Amanraj Claire, Vanessa Castillo, Moises Hernandez, Hana Russo, Jason Duran, Laura E Crotty Alexander, Ann Tipps, Grace Lin, Patricia A Thistlethwaite, Ranajoy Chattopadhyay, Thomas F Rogers, Debashis Sahoo, Pradipta Ghosh, Soumita Das
Formato:	article
Lenguaje:	EN
Publicado:	eLife Sciences Publications Ltd 2021
Materias:	lung organoid SARS-CoV2 disease modeling computational immune response AT2 differentiation Medicine R Science Q Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a2f6ea2e6df643eab8feb143e8860634
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Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

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