Emerging heterogeneous compartments by viruses in single bacterial cells

Here, the authors apply live-cell and in situ fluorescence imaging at the single-molecule level to examine lambda DNA replication in single cells, finding that individual phage DNAs sequester host factors to their own vicinity and confine their replicated DNAs into separate compartments, suggesting...

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Autores principales:	Jimmy T. Trinh, Qiuyan Shao, Jingwen Guan, Lanying Zeng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2f7befa00a34537abb5c606a049bb6b
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spelling	oai:doaj.org-article:a2f7befa00a34537abb5c606a049bb6b2021-12-02T16:25:01ZEmerging heterogeneous compartments by viruses in single bacterial cells10.1038/s41467-020-17515-82041-1723https://doaj.org/article/a2f7befa00a34537abb5c606a049bb6b2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17515-8https://doaj.org/toc/2041-1723Here, the authors apply live-cell and in situ fluorescence imaging at the single-molecule level to examine lambda DNA replication in single cells, finding that individual phage DNAs sequester host factors to their own vicinity and confine their replicated DNAs into separate compartments, suggesting that phage decision-making transcripts are spatially organized in separate compartments to allow distinct subcellular decisions to develop.Jimmy T. TrinhQiuyan ShaoJingwen GuanLanying ZengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jimmy T. Trinh Qiuyan Shao Jingwen Guan Lanying Zeng Emerging heterogeneous compartments by viruses in single bacterial cells
description	Here, the authors apply live-cell and in situ fluorescence imaging at the single-molecule level to examine lambda DNA replication in single cells, finding that individual phage DNAs sequester host factors to their own vicinity and confine their replicated DNAs into separate compartments, suggesting that phage decision-making transcripts are spatially organized in separate compartments to allow distinct subcellular decisions to develop.
format	article
author	Jimmy T. Trinh Qiuyan Shao Jingwen Guan Lanying Zeng
author_facet	Jimmy T. Trinh Qiuyan Shao Jingwen Guan Lanying Zeng
author_sort	Jimmy T. Trinh
title	Emerging heterogeneous compartments by viruses in single bacterial cells
title_short	Emerging heterogeneous compartments by viruses in single bacterial cells
title_full	Emerging heterogeneous compartments by viruses in single bacterial cells
title_fullStr	Emerging heterogeneous compartments by viruses in single bacterial cells
title_full_unstemmed	Emerging heterogeneous compartments by viruses in single bacterial cells
title_sort	emerging heterogeneous compartments by viruses in single bacterial cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a2f7befa00a34537abb5c606a049bb6b
work_keys_str_mv	AT jimmyttrinh emergingheterogeneouscompartmentsbyvirusesinsinglebacterialcells AT qiuyanshao emergingheterogeneouscompartmentsbyvirusesinsinglebacterialcells AT jingwenguan emergingheterogeneouscompartmentsbyvirusesinsinglebacterialcells AT lanyingzeng emergingheterogeneouscompartmentsbyvirusesinsinglebacterialcells
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Emerging heterogeneous compartments by viruses in single bacterial cells

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