The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia.

The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia.

Ecotropic viral integration site-1 (EVI1) is one of the candidate oncogenes for human acute myeloid leukemia (AML) with chromosomal alterations at 3q26. High EVI1 expression (EVI1(high)) is a risk factor for AML with poor outcome. Using DNA microarray analysis, we previously identified that integrin...

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Autores principales: Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a2f90864bbf54dcfa024ff6935b273d8
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