Oleanolic Acid Enhances Mesenchymal Stromal Cell Osteogenic Potential by Inhibition of Notch Signaling

Oleanolic Acid Enhances Mesenchymal Stromal Cell Osteogenic Potential by Inhibition of Notch Signaling

Abstract Oleanolic acid (OA), a pentacyclic triterpenoid, has been shown to modulate multiple signaling pathways in a variety of cell linages. But the mechanisms underlying OA-mediated mesenchymal stromal cell (MSC) osteogenic differentiation are not known. In this study, we examined effects of OA o...

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Autores principales: Bing Shu, Yongjian Zhao, Yongjun Wang, Guangxi Wang, Xifu Shang, Michael Britt, Margaret Olmedo, Marjorie Chelly, Massimo Max Morandi, Shane Barton, Yufeng Dong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/a3021b4744194ade8c2f5073b2a36a94
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