Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study

Introduction: Gallbladder diseases are prevalent worldwide and present with a diverse histopathological spectrum. Mucosal irritation and chronic inflammation is considered as an important etiological factor for the mechanical or functional dysfunction of emptying of the gallbladder. This study aim...

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Autores principales:	Dilasma Ghartimagar, Manish Kiran Shrestha, Adarsh Jhunjhunwala, Arnab Ghosh, Sushma Thapa, Sudeep Regmi, Om Praksah Talwar
Formato:	article
Lenguaje:	EN
Publicado:	Nepal Medical Association 2021
Materias:	cholecystitis cholelithiasis gallbladder metaplasia pyloric Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a30e00a9a191424a9705081adc95b743
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spelling	oai:doaj.org-article:a30e00a9a191424a9705081adc95b7432021-11-07T19:11:55ZNon-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study10.31729/jnma.58610028-27151815-672Xhttps://doaj.org/article/a30e00a9a191424a9705081adc95b7432021-10-01T00:00:00Zhttps://www.jnma.com.np/jnma/index.php/jnma/article/view/5861https://doaj.org/toc/0028-2715https://doaj.org/toc/1815-672X Introduction: Gallbladder diseases are prevalent worldwide and present with a diverse histopathological spectrum. Mucosal irritation and chronic inflammation is considered as an important etiological factor for the mechanical or functional dysfunction of emptying of the gallbladder. This study aims to find the prevalence of non-neoplastic lesions of gallbladder among cholecystectomy specimens of a tertiary care center. Methods: A descriptive cross-sectional study was conducted in the Department of Pathology, of a tertiary care center from January 2005 to December 2020. Ethical approval was taken from the Institutional Review Committee. All the patients who had undergone cholecystectomy procedures which showed non-neoplastic lesions were enrolled in the study. Convenient sampling was done. Statistical Package for Social Sciences version 21 and Microsoft Excel were used for data analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 4914 cholecystectomy specimens, 4852 (98.73%) (95% Confidence Interval= 98.42- 99.04) were non-neoplastic lesions. There were 1252 (25.8%) males and 3600 (74.2%) females with a male to female ratio of 1:2.87. Age ranged from 2 to 89 years with a mean age of 45±14.48 years. Gallbladder lesions were observed maximum in age group 41-50 years with 1200 (24.7%) cases. Among the non-neoplastic lesions, cholecystitis without any specific finding was the most common finding with 3028 (62.4%) cases followed by cholelithiasis with 1478 (30.5%) cases. Conclusions: The prevalence of non-neoplastic lesions of gallbladder is similar to other studies done in similar setings. Female predominance was noted in non-neoplastic lesions. Dilasma GhartimagarManish Kiran ShresthaAdarsh JhunjhunwalaArnab GhoshSushma ThapaSudeep RegmiOm Praksah TalwarNepal Medical AssociationarticlecholecystitischolelithiasisgallbladdermetaplasiapyloricMedicine (General)R5-920ENJournal of Nepal Medical Association, Vol 59, Iss 242 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cholecystitis cholelithiasis gallbladder metaplasia pyloric Medicine (General) R5-920
spellingShingle	cholecystitis cholelithiasis gallbladder metaplasia pyloric Medicine (General) R5-920 Dilasma Ghartimagar Manish Kiran Shrestha Adarsh Jhunjhunwala Arnab Ghosh Sushma Thapa Sudeep Regmi Om Praksah Talwar Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
description	Introduction: Gallbladder diseases are prevalent worldwide and present with a diverse histopathological spectrum. Mucosal irritation and chronic inflammation is considered as an important etiological factor for the mechanical or functional dysfunction of emptying of the gallbladder. This study aims to find the prevalence of non-neoplastic lesions of gallbladder among cholecystectomy specimens of a tertiary care center. Methods: A descriptive cross-sectional study was conducted in the Department of Pathology, of a tertiary care center from January 2005 to December 2020. Ethical approval was taken from the Institutional Review Committee. All the patients who had undergone cholecystectomy procedures which showed non-neoplastic lesions were enrolled in the study. Convenient sampling was done. Statistical Package for Social Sciences version 21 and Microsoft Excel were used for data analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 4914 cholecystectomy specimens, 4852 (98.73%) (95% Confidence Interval= 98.42- 99.04) were non-neoplastic lesions. There were 1252 (25.8%) males and 3600 (74.2%) females with a male to female ratio of 1:2.87. Age ranged from 2 to 89 years with a mean age of 45±14.48 years. Gallbladder lesions were observed maximum in age group 41-50 years with 1200 (24.7%) cases. Among the non-neoplastic lesions, cholecystitis without any specific finding was the most common finding with 3028 (62.4%) cases followed by cholelithiasis with 1478 (30.5%) cases. Conclusions: The prevalence of non-neoplastic lesions of gallbladder is similar to other studies done in similar setings. Female predominance was noted in non-neoplastic lesions.
format	article
author	Dilasma Ghartimagar Manish Kiran Shrestha Adarsh Jhunjhunwala Arnab Ghosh Sushma Thapa Sudeep Regmi Om Praksah Talwar
author_facet	Dilasma Ghartimagar Manish Kiran Shrestha Adarsh Jhunjhunwala Arnab Ghosh Sushma Thapa Sudeep Regmi Om Praksah Talwar
author_sort	Dilasma Ghartimagar
title	Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
title_short	Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
title_full	Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
title_fullStr	Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
title_full_unstemmed	Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study
title_sort	non-neoplastic lesions of gallbladder among cholecystectomy specimens of a tertiary care center: a descriptive cross-sectional study
publisher	Nepal Medical Association
publishDate	2021
url	https://doaj.org/article/a30e00a9a191424a9705081adc95b743
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Non-neoplastic Lesions of Gallbladder Among Cholecystectomy Specimens of a Tertiary Care Center: A Descriptive Cross-sectional Study

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