A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature

The present paper reports the case of a 3 years old, female Bearded Dragon (Pogona vitticeps) presenting lethargy, anorexia, weight loss, and anemia and marked leukocytosis at CBC. The majority of leukocytes were lymphocytic/lymphoblastic cells (97%). Immunocytochemical staining of blood smears mark...

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Autores principales:	Gavazza Alessandra, Galosi Livio, Croce Veronica, Croce Amerio, Genovese Carla, Romano Paolo, Cerquetella Matteo, Rossi Giacomo
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	bearded dragon pogona vitticeps leukemia lymphocytosis review Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/a30ee35f9d7e48b69369b32f0871b70a
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spelling	oai:doaj.org-article:a30ee35f9d7e48b69369b32f0871b70a2021-11-17T21:27:53ZA Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature1820-744810.2478/acve-2019-0030https://doaj.org/article/a30ee35f9d7e48b69369b32f0871b70a2019-09-01T00:00:00Zhttps://doi.org/10.2478/acve-2019-0030https://doaj.org/toc/1820-7448The present paper reports the case of a 3 years old, female Bearded Dragon (Pogona vitticeps) presenting lethargy, anorexia, weight loss, and anemia and marked leukocytosis at CBC. The majority of leukocytes were lymphocytic/lymphoblastic cells (97%). Immunocytochemical staining of blood smears marked for CD3 (neg) and CD79a (pos) suggested immunophenotype B. The patient died after one month from diagnosis. Histology evidenced lymphoid infiltration in the heart, spleen, liver, kidneys and gut. In addition, in the bone marrow a massive infiltration of lymphoid cells confirmed the diagnosis of leukemia. Immunohistochemistry confirmed the CD79a positivity of a large part of infiltrating lymphoid cells indicating a B cells immunophenotype of the neoplastic population. The presence of lymphocytosis and multiorgan infiltration supported the diagnosis of lymphocytic leukemia. Finally, a revision of the literature has also been made.Gavazza AlessandraGalosi LivioCroce VeronicaCroce AmerioGenovese CarlaRomano PaoloCerquetella MatteoRossi GiacomoSciendoarticlebearded dragonpogona vitticepsleukemialymphocytosisreviewVeterinary medicineSF600-1100ENActa Veterinaria, Vol 69, Iss 3, Pp 360-368 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	bearded dragon pogona vitticeps leukemia lymphocytosis review Veterinary medicine SF600-1100
spellingShingle	bearded dragon pogona vitticeps leukemia lymphocytosis review Veterinary medicine SF600-1100 Gavazza Alessandra Galosi Livio Croce Veronica Croce Amerio Genovese Carla Romano Paolo Cerquetella Matteo Rossi Giacomo A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature
description	The present paper reports the case of a 3 years old, female Bearded Dragon (Pogona vitticeps) presenting lethargy, anorexia, weight loss, and anemia and marked leukocytosis at CBC. The majority of leukocytes were lymphocytic/lymphoblastic cells (97%). Immunocytochemical staining of blood smears marked for CD3 (neg) and CD79a (pos) suggested immunophenotype B. The patient died after one month from diagnosis. Histology evidenced lymphoid infiltration in the heart, spleen, liver, kidneys and gut. In addition, in the bone marrow a massive infiltration of lymphoid cells confirmed the diagnosis of leukemia. Immunohistochemistry confirmed the CD79a positivity of a large part of infiltrating lymphoid cells indicating a B cells immunophenotype of the neoplastic population. The presence of lymphocytosis and multiorgan infiltration supported the diagnosis of lymphocytic leukemia. Finally, a revision of the literature has also been made.
format	article
author	Gavazza Alessandra Galosi Livio Croce Veronica Croce Amerio Genovese Carla Romano Paolo Cerquetella Matteo Rossi Giacomo
author_facet	Gavazza Alessandra Galosi Livio Croce Veronica Croce Amerio Genovese Carla Romano Paolo Cerquetella Matteo Rossi Giacomo
author_sort	Gavazza Alessandra
title	A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature
title_short	A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature
title_full	A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature
title_fullStr	A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature
title_full_unstemmed	A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature
title_sort	case of lymphocytic leukemia in a bearded dragon (pogona vitticeps) and a review of literature
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/a30ee35f9d7e48b69369b32f0871b70a
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A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature

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