Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination

Lei Zhang,1,2,* Wendi Yang,1,* Chaohua Hu,3 Qianchao Wang,1 Yunkun Wu1,2 1College of Life Sciences, Fujian Normal University, Fuzhou, China; 2State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China; 3National...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Zhang L, Yang W, Hu C, Wang Q, Wu Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	oral vaccine NP/MP conveyors intestine antibody immune response Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a30f57c93c8b4b339602fd0e44cca3a0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a30f57c93c8b4b339602fd0e44cca3a0
record_format	dspace
spelling	oai:doaj.org-article:a30f57c93c8b4b339602fd0e44cca3a02021-12-02T06:01:39ZProperties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination1178-2013https://doaj.org/article/a30f57c93c8b4b339602fd0e44cca3a02018-05-01T00:00:00Zhttps://www.dovepress.com/properties-and-applications-of-nanoparticlemicroparticle-conveyors-wit-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Lei Zhang,1,2,* Wendi Yang,1,* Chaohua Hu,3 Qianchao Wang,1 Yunkun Wu1,2 1College of Life Sciences, Fujian Normal University, Fuzhou, China; 2State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China; 3National Engineering Research Center for Sugarcane, College of Crop Science, Fujian Agriculture and Forestry University, Fuzhou, China *These authors contributed equally to this work Abstract: Vaccination is one of the most effective approaches in the prevention and control of disease worldwide. Oral vaccination could have wide applications if effective protection cannot be achieved through traditional (eg, parenteral) routes of vaccination. However, oral administration is hampered by the difficulties in transferring vaccines in vivo. This has led to the development of materials such as carriers with potential adjuvant effects. Considering the requirements for selecting adjuvants for oral vaccines as well as the advantages of nanoparticle/microparticle materials as immune effectors and antigen conveyors, synthetic materials could improve the efficiency of oral vaccination. In this review, nanoparticles and microparticles with adjuvant characteristics are described with regard to their potential importance for oral immunization, and some promising and successful modification strategies are summarized. Keywords: oral vaccine, NP/MP conveyors, intestine, antibody, immune responseZhang LYang WHu CWang QWu YDove Medical Pressarticleoral vaccineNP/MP conveyorsintestineantibodyimmune responseMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 2973-2987 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	oral vaccine NP/MP conveyors intestine antibody immune response Medicine (General) R5-920
spellingShingle	oral vaccine NP/MP conveyors intestine antibody immune response Medicine (General) R5-920 Zhang L Yang W Hu C Wang Q Wu Y Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
description	Lei Zhang,1,2,* Wendi Yang,1,* Chaohua Hu,3 Qianchao Wang,1 Yunkun Wu1,2 1College of Life Sciences, Fujian Normal University, Fuzhou, China; 2State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China; 3National Engineering Research Center for Sugarcane, College of Crop Science, Fujian Agriculture and Forestry University, Fuzhou, China *These authors contributed equally to this work Abstract: Vaccination is one of the most effective approaches in the prevention and control of disease worldwide. Oral vaccination could have wide applications if effective protection cannot be achieved through traditional (eg, parenteral) routes of vaccination. However, oral administration is hampered by the difficulties in transferring vaccines in vivo. This has led to the development of materials such as carriers with potential adjuvant effects. Considering the requirements for selecting adjuvants for oral vaccines as well as the advantages of nanoparticle/microparticle materials as immune effectors and antigen conveyors, synthetic materials could improve the efficiency of oral vaccination. In this review, nanoparticles and microparticles with adjuvant characteristics are described with regard to their potential importance for oral immunization, and some promising and successful modification strategies are summarized. Keywords: oral vaccine, NP/MP conveyors, intestine, antibody, immune response
format	article
author	Zhang L Yang W Hu C Wang Q Wu Y
author_facet	Zhang L Yang W Hu C Wang Q Wu Y
author_sort	Zhang L
title	Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
title_short	Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
title_full	Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
title_fullStr	Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
title_full_unstemmed	Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
title_sort	properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/a30f57c93c8b4b339602fd0e44cca3a0
work_keys_str_mv	AT zhangl propertiesandapplicationsofnanoparticlemicroparticleconveyorswithadjuvantcharacteristicssuitablefororalvaccination AT yangw propertiesandapplicationsofnanoparticlemicroparticleconveyorswithadjuvantcharacteristicssuitablefororalvaccination AT huc propertiesandapplicationsofnanoparticlemicroparticleconveyorswithadjuvantcharacteristicssuitablefororalvaccination AT wangq propertiesandapplicationsofnanoparticlemicroparticleconveyorswithadjuvantcharacteristicssuitablefororalvaccination AT wuy propertiesandapplicationsofnanoparticlemicroparticleconveyorswithadjuvantcharacteristicssuitablefororalvaccination
_version_	1718400126028873728

Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination

Ejemplares similares