Transcription initiation at a consensus bacterial promoter proceeds via a ‘bind-unwind-load-and-lock’ mechanism
Transcription initiation starts with unwinding of promoter DNA by RNA polymerase (RNAP) to form a catalytically competent RNAP-promoter complex (RPo). Despite extensive study, the mechanism of promoter unwinding has remained unclear, in part due to the transient nature of intermediates on path to RP...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
eLife Sciences Publications Ltd
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/a30f5b4d3ff2433d975fec7b77a92d47 |
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