An analytic approximation of the feasible space of metabolic networks
Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, en...
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Nature Portfolio
2017
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oai:doaj.org-article:a310c3829c1b4c4c9dfde675741de8912021-12-02T14:42:20ZAn analytic approximation of the feasible space of metabolic networks10.1038/ncomms149152041-1723https://doaj.org/article/a310c3829c1b4c4c9dfde675741de8912017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14915https://doaj.org/toc/2041-1723Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, enabling more accurate analysis under a wide range of conditions of interest.Alfredo BraunsteinAnna Paola MuntoniAndrea PagnaniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Alfredo Braunstein Anna Paola Muntoni Andrea Pagnani An analytic approximation of the feasible space of metabolic networks |
description |
Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, enabling more accurate analysis under a wide range of conditions of interest. |
format |
article |
author |
Alfredo Braunstein Anna Paola Muntoni Andrea Pagnani |
author_facet |
Alfredo Braunstein Anna Paola Muntoni Andrea Pagnani |
author_sort |
Alfredo Braunstein |
title |
An analytic approximation of the feasible space of metabolic networks |
title_short |
An analytic approximation of the feasible space of metabolic networks |
title_full |
An analytic approximation of the feasible space of metabolic networks |
title_fullStr |
An analytic approximation of the feasible space of metabolic networks |
title_full_unstemmed |
An analytic approximation of the feasible space of metabolic networks |
title_sort |
analytic approximation of the feasible space of metabolic networks |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/a310c3829c1b4c4c9dfde675741de891 |
work_keys_str_mv |
AT alfredobraunstein ananalyticapproximationofthefeasiblespaceofmetabolicnetworks AT annapaolamuntoni ananalyticapproximationofthefeasiblespaceofmetabolicnetworks AT andreapagnani ananalyticapproximationofthefeasiblespaceofmetabolicnetworks AT alfredobraunstein analyticapproximationofthefeasiblespaceofmetabolicnetworks AT annapaolamuntoni analyticapproximationofthefeasiblespaceofmetabolicnetworks AT andreapagnani analyticapproximationofthefeasiblespaceofmetabolicnetworks |
_version_ |
1718389706636394496 |