An analytic approximation of the feasible space of metabolic networks

Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, en...

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Autores principales: Alfredo Braunstein, Anna Paola Muntoni, Andrea Pagnani
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a310c3829c1b4c4c9dfde675741de891
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spelling oai:doaj.org-article:a310c3829c1b4c4c9dfde675741de8912021-12-02T14:42:20ZAn analytic approximation of the feasible space of metabolic networks10.1038/ncomms149152041-1723https://doaj.org/article/a310c3829c1b4c4c9dfde675741de8912017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14915https://doaj.org/toc/2041-1723Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, enabling more accurate analysis under a wide range of conditions of interest.Alfredo BraunsteinAnna Paola MuntoniAndrea PagnaniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alfredo Braunstein
Anna Paola Muntoni
Andrea Pagnani
An analytic approximation of the feasible space of metabolic networks
description Large-scale metabolic models of organisms from microbes to mammals can provide great insight into cellular function, but their analysis remains challenging. Here, the authors provide an approximate analytic method to estimate the feasible solution space for the flux vectors of metabolic networks, enabling more accurate analysis under a wide range of conditions of interest.
format article
author Alfredo Braunstein
Anna Paola Muntoni
Andrea Pagnani
author_facet Alfredo Braunstein
Anna Paola Muntoni
Andrea Pagnani
author_sort Alfredo Braunstein
title An analytic approximation of the feasible space of metabolic networks
title_short An analytic approximation of the feasible space of metabolic networks
title_full An analytic approximation of the feasible space of metabolic networks
title_fullStr An analytic approximation of the feasible space of metabolic networks
title_full_unstemmed An analytic approximation of the feasible space of metabolic networks
title_sort analytic approximation of the feasible space of metabolic networks
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/a310c3829c1b4c4c9dfde675741de891
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