ZASP interacts with the mechanosensing protein Ankrd2 and p53 in the signalling network of striated muscle.
ZASP is a cytoskeletal PDZ-LIM protein predominantly expressed in striated muscle. It forms multiprotein complexes and plays a pivotal role in the structural integrity of sarcomeres. Mutations in the ZASP protein are associated with myofibrillar myopathy, left ventricular non-compaction and dilated...
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Auteurs principaux: | Valentina C Martinelli, W Buck Kyle, Snezana Kojic, Nicola Vitulo, Zhaohui Li, Anna Belgrano, Paolo Maiuri, Lawrence Banks, Matteo Vatta, Giorgio Valle, Georgine Faulkner |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Sujets: | |
Accès en ligne: | https://doaj.org/article/a3314c54bdc94d7eb18d922eb9cc8b75 |
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