Case report and strategies to mitigate passive hemolysis with platelet transfusions in children

Mismatched platelet concentrate transfusion due to inadequately maintained inventories is relatively common and in most instances do not cause any untoward event in adults. The cases of passive hemolysis following a mismatched apheresis platelet transfusion are common but are relatively rare with pl...

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Autores principales:	Merline Augustine, Mohandoss Murugesan, Kaduveettil Gopinathan Gopakumar, T K Jithin
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	abo-incompatible platelet transfusions transfusion reaction Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/a3326c6971a74c74898b2e9feaa4ee8d
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spelling	oai:doaj.org-article:a3326c6971a74c74898b2e9feaa4ee8d2021-11-12T10:08:28ZCase report and strategies to mitigate passive hemolysis with platelet transfusions in children0973-62471998-356510.4103/2589-0603.329648https://doaj.org/article/a3326c6971a74c74898b2e9feaa4ee8d2021-01-01T00:00:00Zhttp://www.ajts.org/article.asp?issn=0973-6247;year=2021;volume=15;issue=2;spage=229;epage=232;aulast=Augustinehttps://doaj.org/toc/0973-6247https://doaj.org/toc/1998-3565Mismatched platelet concentrate transfusion due to inadequately maintained inventories is relatively common and in most instances do not cause any untoward event in adults. The cases of passive hemolysis following a mismatched apheresis platelet transfusion are common but are relatively rare with platelet concentrates. We report here a case of a nine year old boy who received three units of mismatched platelet concentrates(PC) followed by acute hemolysis. On further investigation, one of the donors of the PC, who was typed as O positive, found to have high anti-A and anti-B titres of 1:128. This highlights the importance of matched platelet transfusions or modifying the product in pediatric setting, who are susceptible for passive hemolysis.Merline AugustineMohandoss MurugesanKaduveettil Gopinathan GopakumarT K JithinWolters Kluwer Medknow Publicationsarticleabo-incompatibleplatelet transfusionstransfusion reactionDiseases of the blood and blood-forming organsRC633-647.5ENAsian Journal of Transfusion Science, Vol 15, Iss 2, Pp 229-232 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	abo-incompatible platelet transfusions transfusion reaction Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	abo-incompatible platelet transfusions transfusion reaction Diseases of the blood and blood-forming organs RC633-647.5 Merline Augustine Mohandoss Murugesan Kaduveettil Gopinathan Gopakumar T K Jithin Case report and strategies to mitigate passive hemolysis with platelet transfusions in children
description	Mismatched platelet concentrate transfusion due to inadequately maintained inventories is relatively common and in most instances do not cause any untoward event in adults. The cases of passive hemolysis following a mismatched apheresis platelet transfusion are common but are relatively rare with platelet concentrates. We report here a case of a nine year old boy who received three units of mismatched platelet concentrates(PC) followed by acute hemolysis. On further investigation, one of the donors of the PC, who was typed as O positive, found to have high anti-A and anti-B titres of 1:128. This highlights the importance of matched platelet transfusions or modifying the product in pediatric setting, who are susceptible for passive hemolysis.
format	article
author	Merline Augustine Mohandoss Murugesan Kaduveettil Gopinathan Gopakumar T K Jithin
author_facet	Merline Augustine Mohandoss Murugesan Kaduveettil Gopinathan Gopakumar T K Jithin
author_sort	Merline Augustine
title	Case report and strategies to mitigate passive hemolysis with platelet transfusions in children
title_short	Case report and strategies to mitigate passive hemolysis with platelet transfusions in children
title_full	Case report and strategies to mitigate passive hemolysis with platelet transfusions in children
title_fullStr	Case report and strategies to mitigate passive hemolysis with platelet transfusions in children
title_full_unstemmed	Case report and strategies to mitigate passive hemolysis with platelet transfusions in children
title_sort	case report and strategies to mitigate passive hemolysis with platelet transfusions in children
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/a3326c6971a74c74898b2e9feaa4ee8d
work_keys_str_mv	AT merlineaugustine casereportandstrategiestomitigatepassivehemolysiswithplatelettransfusionsinchildren AT mohandossmurugesan casereportandstrategiestomitigatepassivehemolysiswithplatelettransfusionsinchildren AT kaduveettilgopinathangopakumar casereportandstrategiestomitigatepassivehemolysiswithplatelettransfusionsinchildren AT tkjithin casereportandstrategiestomitigatepassivehemolysiswithplatelettransfusionsinchildren
_version_	1718431068190670848

Case report and strategies to mitigate passive hemolysis with platelet transfusions in children

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