Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

A common failure of many cancer treatments is attributed to the resistance imparted by tumour hypoxia. Here, the authors report on the generic synthesis of small-sized hollow mesoporous organosilica nanoparticles which are designed for oxygen-independent X-ray-activated synergistic therapy.

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Autores principales: Wenpei Fan, Nan Lu, Zheyu Shen, Wei Tang, Bo Shen, Zhaowen Cui, Lingling Shan, Zhen Yang, Zhantong Wang, Orit Jacobson, Zijian Zhou, Yijing Liu, Ping Hu, Weijing Yang, Jibin Song, Yang Zhang, Liwen Zhang, Niveen M. Khashab, Maria A. Aronova, Guangming Lu, Xiaoyuan Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a33428d6ae6947ed8bb47a3b9835cc6e
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spelling oai:doaj.org-article:a33428d6ae6947ed8bb47a3b9835cc6e2021-12-02T16:57:22ZGeneric synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy10.1038/s41467-019-09158-12041-1723https://doaj.org/article/a33428d6ae6947ed8bb47a3b9835cc6e2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09158-1https://doaj.org/toc/2041-1723A common failure of many cancer treatments is attributed to the resistance imparted by tumour hypoxia. Here, the authors report on the generic synthesis of small-sized hollow mesoporous organosilica nanoparticles which are designed for oxygen-independent X-ray-activated synergistic therapy.Wenpei FanNan LuZheyu ShenWei TangBo ShenZhaowen CuiLingling ShanZhen YangZhantong WangOrit JacobsonZijian ZhouYijing LiuPing HuWeijing YangJibin SongYang ZhangLiwen ZhangNiveen M. KhashabMaria A. AronovaGuangming LuXiaoyuan ChenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wenpei Fan
Nan Lu
Zheyu Shen
Wei Tang
Bo Shen
Zhaowen Cui
Lingling Shan
Zhen Yang
Zhantong Wang
Orit Jacobson
Zijian Zhou
Yijing Liu
Ping Hu
Weijing Yang
Jibin Song
Yang Zhang
Liwen Zhang
Niveen M. Khashab
Maria A. Aronova
Guangming Lu
Xiaoyuan Chen
Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy
description A common failure of many cancer treatments is attributed to the resistance imparted by tumour hypoxia. Here, the authors report on the generic synthesis of small-sized hollow mesoporous organosilica nanoparticles which are designed for oxygen-independent X-ray-activated synergistic therapy.
format article
author Wenpei Fan
Nan Lu
Zheyu Shen
Wei Tang
Bo Shen
Zhaowen Cui
Lingling Shan
Zhen Yang
Zhantong Wang
Orit Jacobson
Zijian Zhou
Yijing Liu
Ping Hu
Weijing Yang
Jibin Song
Yang Zhang
Liwen Zhang
Niveen M. Khashab
Maria A. Aronova
Guangming Lu
Xiaoyuan Chen
author_facet Wenpei Fan
Nan Lu
Zheyu Shen
Wei Tang
Bo Shen
Zhaowen Cui
Lingling Shan
Zhen Yang
Zhantong Wang
Orit Jacobson
Zijian Zhou
Yijing Liu
Ping Hu
Weijing Yang
Jibin Song
Yang Zhang
Liwen Zhang
Niveen M. Khashab
Maria A. Aronova
Guangming Lu
Xiaoyuan Chen
author_sort Wenpei Fan
title Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy
title_short Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy
title_full Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy
title_fullStr Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy
title_full_unstemmed Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy
title_sort generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent x-ray-activated synergistic therapy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/a33428d6ae6947ed8bb47a3b9835cc6e
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