Effects of sildenafil on the gastrocnemius and cardiac muscles of rats in a model of prolonged moderate exercise training.

Moderate exercise training improves energetic metabolism, tissue perfusion and induces cardiac and skeletal muscle remodeling. Sildenafil, a potent phosphodiesterase-5 inhibitor used to treat erectile dysfunction, reduces infarct size and increases tissue oxygenation in experimental models of cardio...

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Autores principales: Barbara Rinaldi, Maria Donniacuo, Loredana Sodano, Giulia Gritti, Simona Signoriello, Elisabetta Parretta, Liberato Berrino, Konrad Urbanek, Annalisa Capuano, Francesco Rossi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a33ba69c381749b48404ab2ebf2bb748
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