Effects of sildenafil on the gastrocnemius and cardiac muscles of rats in a model of prolonged moderate exercise training.
Moderate exercise training improves energetic metabolism, tissue perfusion and induces cardiac and skeletal muscle remodeling. Sildenafil, a potent phosphodiesterase-5 inhibitor used to treat erectile dysfunction, reduces infarct size and increases tissue oxygenation in experimental models of cardio...
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Autores principales: | Barbara Rinaldi, Maria Donniacuo, Loredana Sodano, Giulia Gritti, Simona Signoriello, Elisabetta Parretta, Liberato Berrino, Konrad Urbanek, Annalisa Capuano, Francesco Rossi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/a33ba69c381749b48404ab2ebf2bb748 |
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