A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of...
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De Gruyter
2020
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oai:doaj.org-article:a340b676ce7e4946926a188e188c62e72021-12-05T14:10:42ZA method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography2364-550410.1515/cdbme-2020-3013https://doaj.org/article/a340b676ce7e4946926a188e188c62e72020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3013https://doaj.org/toc/2364-5504Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of porcine coronary arteries via OCT is described. Diameter measurements based on OCT imaging were performed during consecutive pressurization of a porcine coronary artery from 40 to 200 mmHg in a physiological environment. The test results indicate that the radial compliance depends on the specific segment of the artery as well as the pressure range considered. The revealed compliance data can be used for numerical simulations of the vascular tissue as well as for optimization of in vitro test setups for pulsatile testing of vascular implants.Brandt-Wunderlich ChristophBonin FranziskaSchmidt WolframGrabow NielsSchmitz Klaus- PeterGroßmann SwenStiehm MichaelSchmitz Klaus-PeterSiewert StefanÖner AlperDe Gruyterarticleradial complianceoptical coherence tomographyoctcoronary arteryex vivoMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 48-51 (2020) |
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radial compliance optical coherence tomography oct coronary artery ex vivo Medicine R |
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radial compliance optical coherence tomography oct coronary artery ex vivo Medicine R Brandt-Wunderlich Christoph Bonin Franziska Schmidt Wolfram Grabow Niels Schmitz Klaus- Peter Großmann Swen Stiehm Michael Schmitz Klaus-Peter Siewert Stefan Öner Alper A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
description |
Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of porcine coronary arteries via OCT is described. Diameter measurements based on OCT imaging were performed during consecutive pressurization of a porcine coronary artery from 40 to 200 mmHg in a physiological environment. The test results indicate that the radial compliance depends on the specific segment of the artery as well as the pressure range considered. The revealed compliance data can be used for numerical simulations of the vascular tissue as well as for optimization of in vitro test setups for pulsatile testing of vascular implants. |
format |
article |
author |
Brandt-Wunderlich Christoph Bonin Franziska Schmidt Wolfram Grabow Niels Schmitz Klaus- Peter Großmann Swen Stiehm Michael Schmitz Klaus-Peter Siewert Stefan Öner Alper |
author_facet |
Brandt-Wunderlich Christoph Bonin Franziska Schmidt Wolfram Grabow Niels Schmitz Klaus- Peter Großmann Swen Stiehm Michael Schmitz Klaus-Peter Siewert Stefan Öner Alper |
author_sort |
Brandt-Wunderlich Christoph |
title |
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
title_short |
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
title_full |
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
title_fullStr |
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
title_full_unstemmed |
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
title_sort |
method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography |
publisher |
De Gruyter |
publishDate |
2020 |
url |
https://doaj.org/article/a340b676ce7e4946926a188e188c62e7 |
work_keys_str_mv |
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