A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography

Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of...

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Autores principales: Brandt-Wunderlich Christoph, Bonin Franziska, Schmidt Wolfram, Grabow Niels, Schmitz Klaus- Peter, Großmann Swen, Stiehm Michael, Schmitz Klaus-Peter, Siewert Stefan, Öner Alper
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Lenguaje:EN
Publicado: De Gruyter 2020
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Acceso en línea:https://doaj.org/article/a340b676ce7e4946926a188e188c62e7
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spelling oai:doaj.org-article:a340b676ce7e4946926a188e188c62e72021-12-05T14:10:42ZA method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography2364-550410.1515/cdbme-2020-3013https://doaj.org/article/a340b676ce7e4946926a188e188c62e72020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3013https://doaj.org/toc/2364-5504Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of porcine coronary arteries via OCT is described. Diameter measurements based on OCT imaging were performed during consecutive pressurization of a porcine coronary artery from 40 to 200 mmHg in a physiological environment. The test results indicate that the radial compliance depends on the specific segment of the artery as well as the pressure range considered. The revealed compliance data can be used for numerical simulations of the vascular tissue as well as for optimization of in vitro test setups for pulsatile testing of vascular implants.Brandt-Wunderlich ChristophBonin FranziskaSchmidt WolframGrabow NielsSchmitz Klaus- PeterGroßmann SwenStiehm MichaelSchmitz Klaus-PeterSiewert StefanÖner AlperDe Gruyterarticleradial complianceoptical coherence tomographyoctcoronary arteryex vivoMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 48-51 (2020)
institution DOAJ
collection DOAJ
language EN
topic radial compliance
optical coherence tomography
oct
coronary artery
ex vivo
Medicine
R
spellingShingle radial compliance
optical coherence tomography
oct
coronary artery
ex vivo
Medicine
R
Brandt-Wunderlich Christoph
Bonin Franziska
Schmidt Wolfram
Grabow Niels
Schmitz Klaus- Peter
Großmann Swen
Stiehm Michael
Schmitz Klaus-Peter
Siewert Stefan
Öner Alper
A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
description Optical coherence tomography (OCT) as imaging method is widely used in ophthalmology, oncology and cardiology. For intravascular imaging the OCT is used for pre-interventional as well as post-procedural assessments. Within the current study a test setup for ex vivo determination of the compliance of porcine coronary arteries via OCT is described. Diameter measurements based on OCT imaging were performed during consecutive pressurization of a porcine coronary artery from 40 to 200 mmHg in a physiological environment. The test results indicate that the radial compliance depends on the specific segment of the artery as well as the pressure range considered. The revealed compliance data can be used for numerical simulations of the vascular tissue as well as for optimization of in vitro test setups for pulsatile testing of vascular implants.
format article
author Brandt-Wunderlich Christoph
Bonin Franziska
Schmidt Wolfram
Grabow Niels
Schmitz Klaus- Peter
Großmann Swen
Stiehm Michael
Schmitz Klaus-Peter
Siewert Stefan
Öner Alper
author_facet Brandt-Wunderlich Christoph
Bonin Franziska
Schmidt Wolfram
Grabow Niels
Schmitz Klaus- Peter
Großmann Swen
Stiehm Michael
Schmitz Klaus-Peter
Siewert Stefan
Öner Alper
author_sort Brandt-Wunderlich Christoph
title A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
title_short A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
title_full A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
title_fullStr A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
title_full_unstemmed A method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
title_sort method to determine the radial compliance of porcine coronary arteries ex vivo via optical coherence tomography
publisher De Gruyter
publishDate 2020
url https://doaj.org/article/a340b676ce7e4946926a188e188c62e7
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