Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription

The molecular mechanisms of memory storage remain poorly understood. In this study, authors describe a new mechanism that regulates the cellular patterns of early response gene signaling during learning via the recruitment of two functionally redundant nuclear repressors, class IIa histone deacetyla...

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Autores principales: Yongchuan Zhu, Min Huang, Eric Bushong, Sebastien Phan, Marco Uytiepo, Elizabeth Beutter, Daniel Boemer, Kristin Tsui, Mark Ellisman, Anton Maximov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a3516b0fa6ed4f2a9969586cc281ce01
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