Unmasking GluN1/GluN3A excitatory glycine NMDA receptors

Excitatory glycine GluN1/GluN3A receptors are atypical NMDARs that have been difficult to study. Here the authors identify new properties of these receptors, including potentiation by the GluN1 antagonist CGP-78608 that allows detection of functional GluN1/GluN3A receptors in the juvenile brain.

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Detalles Bibliográficos
Autores principales:	Teddy Grand, Sarah Abi Gerges, Mélissa David, Marco A. Diana, Pierre Paoletti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a35def0fe6364fabae0dd780be3a84b4
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spelling	oai:doaj.org-article:a35def0fe6364fabae0dd780be3a84b42021-12-02T14:41:27ZUnmasking GluN1/GluN3A excitatory glycine NMDA receptors10.1038/s41467-018-07236-42041-1723https://doaj.org/article/a35def0fe6364fabae0dd780be3a84b42018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07236-4https://doaj.org/toc/2041-1723Excitatory glycine GluN1/GluN3A receptors are atypical NMDARs that have been difficult to study. Here the authors identify new properties of these receptors, including potentiation by the GluN1 antagonist CGP-78608 that allows detection of functional GluN1/GluN3A receptors in the juvenile brain.Teddy GrandSarah Abi GergesMélissa DavidMarco A. DianaPierre PaolettiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Teddy Grand Sarah Abi Gerges Mélissa David Marco A. Diana Pierre Paoletti Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
description	Excitatory glycine GluN1/GluN3A receptors are atypical NMDARs that have been difficult to study. Here the authors identify new properties of these receptors, including potentiation by the GluN1 antagonist CGP-78608 that allows detection of functional GluN1/GluN3A receptors in the juvenile brain.
format	article
author	Teddy Grand Sarah Abi Gerges Mélissa David Marco A. Diana Pierre Paoletti
author_facet	Teddy Grand Sarah Abi Gerges Mélissa David Marco A. Diana Pierre Paoletti
author_sort	Teddy Grand
title	Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
title_short	Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
title_full	Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
title_fullStr	Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
title_full_unstemmed	Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
title_sort	unmasking glun1/glun3a excitatory glycine nmda receptors
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a35def0fe6364fabae0dd780be3a84b4
work_keys_str_mv	AT teddygrand unmaskingglun1glun3aexcitatoryglycinenmdareceptors AT sarahabigerges unmaskingglun1glun3aexcitatoryglycinenmdareceptors AT melissadavid unmaskingglun1glun3aexcitatoryglycinenmdareceptors AT marcoadiana unmaskingglun1glun3aexcitatoryglycinenmdareceptors AT pierrepaoletti unmaskingglun1glun3aexcitatoryglycinenmdareceptors
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Unmasking GluN1/GluN3A excitatory glycine NMDA receptors

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