A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells

Self-renewal and pluripotency of human embryonic stem cells (hESCs) depends upon the function of the transcription factor OCT4. Here, the authors identified proteins associated with the OCT4 enhancer, notably ZNF207 that maintains both pluripotency and differentiation towards ectoderm through isofor...

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Autores principales:	Fang Fang, Ninuo Xia, Benjamin Angulo, Joseph Carey, Zackery Cady, Jens Durruthy-Durruthy, Theo Bennett, Vittorio Sebastiano, Renee A. Reijo Pera
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a35e6e487bc6412fa338cd4e9f76670f
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spelling	oai:doaj.org-article:a35e6e487bc6412fa338cd4e9f76670f2021-12-02T15:34:15ZA distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells10.1038/s41467-018-06908-52041-1723https://doaj.org/article/a35e6e487bc6412fa338cd4e9f76670f2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06908-5https://doaj.org/toc/2041-1723Self-renewal and pluripotency of human embryonic stem cells (hESCs) depends upon the function of the transcription factor OCT4. Here, the authors identified proteins associated with the OCT4 enhancer, notably ZNF207 that maintains both pluripotency and differentiation towards ectoderm through isoform switching.Fang FangNinuo XiaBenjamin AnguloJoseph CareyZackery CadyJens Durruthy-DurruthyTheo BennettVittorio SebastianoRenee A. Reijo PeraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fang Fang Ninuo Xia Benjamin Angulo Joseph Carey Zackery Cady Jens Durruthy-Durruthy Theo Bennett Vittorio Sebastiano Renee A. Reijo Pera A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells
description	Self-renewal and pluripotency of human embryonic stem cells (hESCs) depends upon the function of the transcription factor OCT4. Here, the authors identified proteins associated with the OCT4 enhancer, notably ZNF207 that maintains both pluripotency and differentiation towards ectoderm through isoform switching.
format	article
author	Fang Fang Ninuo Xia Benjamin Angulo Joseph Carey Zackery Cady Jens Durruthy-Durruthy Theo Bennett Vittorio Sebastiano Renee A. Reijo Pera
author_facet	Fang Fang Ninuo Xia Benjamin Angulo Joseph Carey Zackery Cady Jens Durruthy-Durruthy Theo Bennett Vittorio Sebastiano Renee A. Reijo Pera
author_sort	Fang Fang
title	A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells
title_short	A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells
title_full	A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells
title_fullStr	A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells
title_full_unstemmed	A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells
title_sort	distinct isoform of znf207 controls self-renewal and pluripotency of human embryonic stem cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a35e6e487bc6412fa338cd4e9f76670f
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A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells

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