A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells

A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells

Self-renewal and pluripotency of human embryonic stem cells (hESCs) depends upon the function of the transcription factor OCT4. Here, the authors identified proteins associated with the OCT4 enhancer, notably ZNF207 that maintains both pluripotency and differentiation towards ectoderm through isofor...

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Autores principales: Fang Fang, Ninuo Xia, Benjamin Angulo, Joseph Carey, Zackery Cady, Jens Durruthy-Durruthy, Theo Bennett, Vittorio Sebastiano, Renee A. Reijo Pera
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/a35e6e487bc6412fa338cd4e9f76670f
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