Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.

<h4>Background</h4>The aggressiveness of melanoma tumors is likely to rely on their well-recognized heterogeneity and plasticity. Melanoma comprises multi-subpopulations of cancer cells some of which may possess stem cell-like properties. Although useful, the sphere-formation assay to id...

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Main Authors: Kiran Ramgolam, Jessica Lauriol, Claude Lalou, Laura Lauden, Laurence Michel, Pierre de la Grange, Abdel-Majid Khatib, Fawzi Aoudjit, Dominique Charron, Catherine Alcaide-Loridan, Reem Al-Daccak
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
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Online Access:https://doaj.org/article/a36cdd4d0a6a448182064f87b8ed2de0
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