INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION

Abstract. Patients with exacerbation of chronic herpesvirus infection were subjected to immunocorrection therapy. In the course of treatment, time-dependent correlations were found between the changes in production of IFNγ, IL-1β and IL-6, and initial level of IFNγ. The patients with high initial co...

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Autores principales:	O. O. Obukhova, A. N. Trunov, A. P. Shvajuk, O. M. Gorbenko, L. A. Trunova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	herpesvirus infection immunocorrection cytokines ifnγ il-1β il-6 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/a37925d2b3ca4ba49beac27ad8744636
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spelling	oai:doaj.org-article:a37925d2b3ca4ba49beac27ad87446362021-11-18T08:03:38ZINTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION1563-06252313-741X10.15789/1563-0625-2008-2-3-283-290https://doaj.org/article/a37925d2b3ca4ba49beac27ad87446362014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/174https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Patients with exacerbation of chronic herpesvirus infection were subjected to immunocorrection therapy. In the course of treatment, time-dependent correlations were found between the changes in production of IFNγ, IL-1β and IL-6, and initial level of IFNγ. The patients with high initial concentrations of IFNγ did also exhibit above-normal initial IL-1Β and IL-6 values, as compared to appropriate parameters for a sub-group with low IFNγ levels. In the course of immunocorrection with Echinacea, all the patients showed increase in IFNγ levels. However, due to initially low IFNγ values, its increase was more pronounced than in persons with high background levels of IFNγ. Dynamics of IL-1Β decrease and changes in IL-6 concentrations were more expressed in cases of higher initial levels of these cytokines. The alterations revealed for IFNγ, IL-1Β and IL-6 levels confirm that immunocorrection with Echinacea causes reduced intensity of inflammation and activation of antiviral immune response. (Med. Immunol., 2008, vol. 10, N 2-3, pp 283-290).O. O. ObukhovaA. N. TrunovA. P. ShvajukO. M. GorbenkoL. A. TrunovaSPb RAACIarticleherpesvirus infectionimmunocorrectioncytokinesifnγil-1βil-6Immunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 2-3, Pp 283-290 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	herpesvirus infection immunocorrection cytokines ifnγ il-1β il-6 Immunologic diseases. Allergy RC581-607
spellingShingle	herpesvirus infection immunocorrection cytokines ifnγ il-1β il-6 Immunologic diseases. Allergy RC581-607 O. O. Obukhova A. N. Trunov A. P. Shvajuk O. M. Gorbenko L. A. Trunova INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION
description	Abstract. Patients with exacerbation of chronic herpesvirus infection were subjected to immunocorrection therapy. In the course of treatment, time-dependent correlations were found between the changes in production of IFNγ, IL-1β and IL-6, and initial level of IFNγ. The patients with high initial concentrations of IFNγ did also exhibit above-normal initial IL-1Β and IL-6 values, as compared to appropriate parameters for a sub-group with low IFNγ levels. In the course of immunocorrection with Echinacea, all the patients showed increase in IFNγ levels. However, due to initially low IFNγ values, its increase was more pronounced than in persons with high background levels of IFNγ. Dynamics of IL-1Β decrease and changes in IL-6 concentrations were more expressed in cases of higher initial levels of these cytokines. The alterations revealed for IFNγ, IL-1Β and IL-6 levels confirm that immunocorrection with Echinacea causes reduced intensity of inflammation and activation of antiviral immune response. (Med. Immunol., 2008, vol. 10, N 2-3, pp 283-290).
format	article
author	O. O. Obukhova A. N. Trunov A. P. Shvajuk O. M. Gorbenko L. A. Trunova
author_facet	O. O. Obukhova A. N. Trunov A. P. Shvajuk O. M. Gorbenko L. A. Trunova
author_sort	O. O. Obukhova
title	INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION
title_short	INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION
title_full	INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION
title_fullStr	INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION
title_full_unstemmed	INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION
title_sort	interrelations of cytokine production in the course of immunocorrection with echinacea for reactivation of herpesvirus infection
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/a37925d2b3ca4ba49beac27ad8744636
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INTERRELATIONS OF CYTOKINE PRODUCTION IN THE COURSE OF IMMUNOCORRECTION WITH ECHINACEA FOR REACTIVATION OF HERPESVIRUS INFECTION

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