Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy

Lucas Brandolt Farias,1,2 Daniel Lavinsky,1,2 Camila Zanella Benfica,1,2 Monica Oliveira da Silva,1,2 Jacó Lavisnky,1,2 Luis Henrique Canani2,3 1Department of Ophthalmology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil; 2Ophthalmology Section, Hospital de Clín...

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Autores principales:	Farias LB, Lavinsky D, Benfica CZ, da Silva MO, Lavinsky J, Canani LH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Choroidal thickness Diabetic choroidopathy Diabetic retinopathy Microalbuminuria Optical coherence tomography Type 2 diabetes. Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/a37d02fa5d23446bbf7b682d42d57dd1
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spelling	oai:doaj.org-article:a37d02fa5d23446bbf7b682d42d57dd12021-12-02T03:35:21ZChanges in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy1177-5483https://doaj.org/article/a37d02fa5d23446bbf7b682d42d57dd12018-08-01T00:00:00Zhttps://www.dovepress.com/changes-in-choroidal-thickness-and-volume-are-related-to-urinary-album-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Lucas Brandolt Farias,1,2 Daniel Lavinsky,1,2 Camila Zanella Benfica,1,2 Monica Oliveira da Silva,1,2 Jacó Lavisnky,1,2 Luis Henrique Canani2,3 1Department of Ophthalmology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil; 2Ophthalmology Section, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; 3Department of Endocrinology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil Purpose: To evaluate choroidal thickness and volume in patients with type 2 diabetes and microalbuminuria using spectral-domain optical coherence tomography. Methods: We recruited 37 diabetic patients without diabetic retinopathy (18 normoalbuminuric and 19 microalbuminuric) and 21 healthy controls. Choroidal thickness and volume were mapped using the automated Early Treatment Diabetic Retinopathy Study grid and a topographic map of thickness was generated manually. Choroid was also measured at 10 locations under the fovea, temporally and nasally. Results: Mean choroidal thickness and volume among patients with diabetes and microalbuminuria was reduced in all locations compared to controls (P<0.05). A sectoral decrease of choroidal thickness and volume was shown between microalbuminuric and normoalbuminuric groups. Conclusion: Choroidal changes were present in type 2 diabetic patients before clinical development of retinopathy. Microalbuminuria was associated with a decrease in choroidal thickness and volume in diabetic patients without diabetic retinopathy. Keywords: choroidal thickness, type 2 diabetes, microalbuminuria, optical coherence tomographyFarias LBLavinsky DBenfica CZda Silva MOLavinsky JCanani LHDove Medical PressarticleChoroidal thicknessDiabetic choroidopathyDiabetic retinopathyMicroalbuminuriaOptical coherence tomographyType 2 diabetes.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 1405-1411 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Choroidal thickness Diabetic choroidopathy Diabetic retinopathy Microalbuminuria Optical coherence tomography Type 2 diabetes. Ophthalmology RE1-994
spellingShingle	Choroidal thickness Diabetic choroidopathy Diabetic retinopathy Microalbuminuria Optical coherence tomography Type 2 diabetes. Ophthalmology RE1-994 Farias LB Lavinsky D Benfica CZ da Silva MO Lavinsky J Canani LH Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
description	Lucas Brandolt Farias,1,2 Daniel Lavinsky,1,2 Camila Zanella Benfica,1,2 Monica Oliveira da Silva,1,2 Jacó Lavisnky,1,2 Luis Henrique Canani2,3 1Department of Ophthalmology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil; 2Ophthalmology Section, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; 3Department of Endocrinology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil Purpose: To evaluate choroidal thickness and volume in patients with type 2 diabetes and microalbuminuria using spectral-domain optical coherence tomography. Methods: We recruited 37 diabetic patients without diabetic retinopathy (18 normoalbuminuric and 19 microalbuminuric) and 21 healthy controls. Choroidal thickness and volume were mapped using the automated Early Treatment Diabetic Retinopathy Study grid and a topographic map of thickness was generated manually. Choroid was also measured at 10 locations under the fovea, temporally and nasally. Results: Mean choroidal thickness and volume among patients with diabetes and microalbuminuria was reduced in all locations compared to controls (P<0.05). A sectoral decrease of choroidal thickness and volume was shown between microalbuminuric and normoalbuminuric groups. Conclusion: Choroidal changes were present in type 2 diabetic patients before clinical development of retinopathy. Microalbuminuria was associated with a decrease in choroidal thickness and volume in diabetic patients without diabetic retinopathy. Keywords: choroidal thickness, type 2 diabetes, microalbuminuria, optical coherence tomography
format	article
author	Farias LB Lavinsky D Benfica CZ da Silva MO Lavinsky J Canani LH
author_facet	Farias LB Lavinsky D Benfica CZ da Silva MO Lavinsky J Canani LH
author_sort	Farias LB
title	Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_short	Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_full	Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_fullStr	Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_full_unstemmed	Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_sort	changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/a37d02fa5d23446bbf7b682d42d57dd1
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_version_	1718401749063041024

Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy

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