A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer

Background and purpose Perfusion Computed Tomography (CTp) is an imaging technique which allows quantitative and qualitative evaluation of tissue perfusion through dynamic CT acquisitions. Since CTp is still considered a research tool in the field of abdominal imaging, the aim of this work is to pro...

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Autores principales:	Nunzia Garbino, Valentina Brancato, Marco Salvatore, Carlo Cavaliere
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/a381231f1fae49729733f8078d5b470b
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spelling	oai:doaj.org-article:a381231f1fae49729733f8078d5b470b2021-12-01T23:35:56ZA Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer1559-325810.1177/15593258211056199https://doaj.org/article/a381231f1fae49729733f8078d5b470b2021-11-01T00:00:00Zhttps://doi.org/10.1177/15593258211056199https://doaj.org/toc/1559-3258Background and purpose Perfusion Computed Tomography (CTp) is an imaging technique which allows quantitative and qualitative evaluation of tissue perfusion through dynamic CT acquisitions. Since CTp is still considered a research tool in the field of abdominal imaging, the aim of this work is to provide a systematic summary of the current literature on CTp in the abdominal region to clarify the role of this technique for abdominal cancer applications. Materials and Methods A systematic literature search of PubMed, Web of Science, and Scopus was performed to identify original articles involving the use of CTp for clinical applications in abdominal cancer since 2011. Studies were included if they reported original data on CTp and investigated the clinical applications of CTp in abdominal cancer. Results Fifty-seven studies were finally included in the study. Most of the included articles (33/57) dealt with CTp at the level of the liver, while a low number of studies investigated CTp for oncologic diseases involving UGI tract (8/57), pancreas (8/57), kidneys (3/57), and colon–rectum (5/57). Conclusions Our study revealed that CTp could be a valuable functional imaging tool in the field of abdominal oncology, particularly as a biomarker for monitoring the response to anti-tumoral treatment.Nunzia GarbinoValentina BrancatoMarco SalvatoreCarlo CavaliereSAGE PublishingarticleTherapeutics. PharmacologyRM1-950ENDose-Response, Vol 19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Therapeutics. Pharmacology RM1-950
spellingShingle	Therapeutics. Pharmacology RM1-950 Nunzia Garbino Valentina Brancato Marco Salvatore Carlo Cavaliere A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer
description	Background and purpose Perfusion Computed Tomography (CTp) is an imaging technique which allows quantitative and qualitative evaluation of tissue perfusion through dynamic CT acquisitions. Since CTp is still considered a research tool in the field of abdominal imaging, the aim of this work is to provide a systematic summary of the current literature on CTp in the abdominal region to clarify the role of this technique for abdominal cancer applications. Materials and Methods A systematic literature search of PubMed, Web of Science, and Scopus was performed to identify original articles involving the use of CTp for clinical applications in abdominal cancer since 2011. Studies were included if they reported original data on CTp and investigated the clinical applications of CTp in abdominal cancer. Results Fifty-seven studies were finally included in the study. Most of the included articles (33/57) dealt with CTp at the level of the liver, while a low number of studies investigated CTp for oncologic diseases involving UGI tract (8/57), pancreas (8/57), kidneys (3/57), and colon–rectum (5/57). Conclusions Our study revealed that CTp could be a valuable functional imaging tool in the field of abdominal oncology, particularly as a biomarker for monitoring the response to anti-tumoral treatment.
format	article
author	Nunzia Garbino Valentina Brancato Marco Salvatore Carlo Cavaliere
author_facet	Nunzia Garbino Valentina Brancato Marco Salvatore Carlo Cavaliere
author_sort	Nunzia Garbino
title	A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer
title_short	A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer
title_full	A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer
title_fullStr	A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer
title_full_unstemmed	A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer
title_sort	systematic review on the role of the perfusion computed tomography in abdominal cancer
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/a381231f1fae49729733f8078d5b470b
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A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer

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