Patient-Derived Cells to Guide Targeted Therapy for Advanced Lung Adenocarcinoma

Abstract Adequate preclinical model and model establishment procedure are required to accelerate translational research in lung cancer. We streamlined a protocol for establishing patient-derived cells (PDC) and identified effective targeted therapies and novel resistance mechanisms using PDCs. We ge...

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Main Authors: Seok-Young Kim, Ji Yeon Lee, Dong Hwi Kim, Hyeong -Seok Joo, Mi Ran Yun, Dongmin Jung, Jiyeon Yun, Seong Gu Heo, Beung -Chul Ahn, Chae Won Park, Kyoung Ho Pyo, You Jin Chun, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/a381d185621a4cc6965c977aa42e9fc1
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