BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters

O-alkylation of carboxylates by alkyl halides has only been observed transiently in enzymatic processes. Here, the authors show a carboxylate alkylating enzyme, BrtB, that catalyzes C-O bond formation between free fatty acids and secondary alkyl chlorides.

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Autores principales:	João P. A. Reis, Sandra A. C. Figueiredo, Maria Lígia Sousa, Pedro N. Leão
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a39484d669af4d91a489e9af1c3336c4
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spelling	oai:doaj.org-article:a39484d669af4d91a489e9af1c3336c42021-12-02T17:31:23ZBrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters10.1038/s41467-020-15302-z2041-1723https://doaj.org/article/a39484d669af4d91a489e9af1c3336c42020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15302-zhttps://doaj.org/toc/2041-1723O-alkylation of carboxylates by alkyl halides has only been observed transiently in enzymatic processes. Here, the authors show a carboxylate alkylating enzyme, BrtB, that catalyzes C-O bond formation between free fatty acids and secondary alkyl chlorides.João P. A. ReisSandra A. C. FigueiredoMaria Lígia SousaPedro N. LeãoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q João P. A. Reis Sandra A. C. Figueiredo Maria Lígia Sousa Pedro N. Leão BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters
description	O-alkylation of carboxylates by alkyl halides has only been observed transiently in enzymatic processes. Here, the authors show a carboxylate alkylating enzyme, BrtB, that catalyzes C-O bond formation between free fatty acids and secondary alkyl chlorides.
format	article
author	João P. A. Reis Sandra A. C. Figueiredo Maria Lígia Sousa Pedro N. Leão
author_facet	João P. A. Reis Sandra A. C. Figueiredo Maria Lígia Sousa Pedro N. Leão
author_sort	João P. A. Reis
title	BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters
title_short	BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters
title_full	BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters
title_fullStr	BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters
title_full_unstemmed	BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters
title_sort	brtb is an o-alkylating enzyme that generates fatty acid-bartoloside esters
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a39484d669af4d91a489e9af1c3336c4
work_keys_str_mv	AT joaopareis brtbisanoalkylatingenzymethatgeneratesfattyacidbartolosideesters AT sandraacfigueiredo brtbisanoalkylatingenzymethatgeneratesfattyacidbartolosideesters AT marialigiasousa brtbisanoalkylatingenzymethatgeneratesfattyacidbartolosideesters AT pedronleao brtbisanoalkylatingenzymethatgeneratesfattyacidbartolosideesters
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BrtB is an O-alkylating enzyme that generates fatty acid-bartoloside esters

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