Benign renal tumors in pediatric age group: Retrospective analysis

Background: Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature. Materials and Methods: Retrospective review of children with benign renal tumors operated between 2006 and...

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Autores principales:	Prema Menon, Katragadda Lakshmi Narasimha Rao, Saalim Nazki, Saswati Behera, Kirti Gupta, Ram Samujh, Shailesh Solanki, Akshay Saxena, Deepak Bansal, Amita Trehan
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	angiomyolipoma congenital mesoblastic nephroma kidney multilocular cystic nephroma nephroureterectomy teratoma Pediatrics RJ1-570 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/a3a6f0a2117b492187e52bdbc696e602
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spelling	oai:doaj.org-article:a3a6f0a2117b492187e52bdbc696e6022021-11-19T10:42:05ZBenign renal tumors in pediatric age group: Retrospective analysis0971-92611998-389110.4103/jiaps.JIAPS_214_20https://doaj.org/article/a3a6f0a2117b492187e52bdbc696e6022021-01-01T00:00:00Zhttp://www.jiaps.com/article.asp?issn=0971-9261;year=2021;volume=26;issue=6;spage=380;epage=392;aulast=Menonhttps://doaj.org/toc/0971-9261https://doaj.org/toc/1998-3891Background: Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature. Materials and Methods: Retrospective review of children with benign renal tumors operated between 2006 and 2018 at one center. Results: Twelve patients (M:F ratio 10:2), age range 3 weeks (31-week gestation) to 13 years presented with large palpable renal swelling (n = 12) and hematuria (n = 3). Computed tomography (CT) scan showed features typical of the tumor. Final histopathology (age group [mean]) showed: multilocular cystic nephroma (MLCN) - n = 5 (41.7%), (11–16 months [13.6]); congenital mesoblastic nephroma (CMN) - n = 4 (33.3%) (classic 1, cellular 3) (0.75–5 months [2.125]); mature cystic teratoma - n = 1 (8.3%): (48 months, in a horseshoe kidney), and angiomyolipoma (AML) - n = 2 (16.7%) (144 months [sporadic] and 156 months [tuberous sclerosis]) One patient with cystic teratoma with no calcification on CT scan received pre-operative chemotherapy as fine-needle aspiration cytology (FNAC) reported malignant small blue cell tumor. Nephroureterectomy with Gerota's fascia could be done easily in all without intraoperative complications. Delay in presentation in MLCN and CMN led to increased symptoms and CT scan changes. All patients did well in 1.5–12 years (median 3 years) follow-up including cellular mesoblastic nephroma. Conclusions: Benign renal tumors often occur in specific age groups but may overlap that of Wilms tumor. Proper interpretation of clinical presentation, CT scan, and FNAC findings help in avoiding preoperative chemotherapy. Upfront nephroureterectomy is curative. Histopathological findings decide further treatment. Children with AML and tuberous sclerosis need lifelong follow-up.Prema MenonKatragadda Lakshmi Narasimha RaoSaalim NazkiSaswati BeheraKirti GuptaRam SamujhShailesh SolankiAkshay SaxenaDeepak BansalAmita TrehanWolters Kluwer Medknow Publicationsarticleangiomyolipomacongenital mesoblastic nephromakidneymultilocular cystic nephromanephroureterectomyteratomaPediatricsRJ1-570SurgeryRD1-811ENJournal of Indian Association of Pediatric Surgeons, Vol 26, Iss 6, Pp 380-392 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	angiomyolipoma congenital mesoblastic nephroma kidney multilocular cystic nephroma nephroureterectomy teratoma Pediatrics RJ1-570 Surgery RD1-811
spellingShingle	angiomyolipoma congenital mesoblastic nephroma kidney multilocular cystic nephroma nephroureterectomy teratoma Pediatrics RJ1-570 Surgery RD1-811 Prema Menon Katragadda Lakshmi Narasimha Rao Saalim Nazki Saswati Behera Kirti Gupta Ram Samujh Shailesh Solanki Akshay Saxena Deepak Bansal Amita Trehan Benign renal tumors in pediatric age group: Retrospective analysis
description	Background: Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature. Materials and Methods: Retrospective review of children with benign renal tumors operated between 2006 and 2018 at one center. Results: Twelve patients (M:F ratio 10:2), age range 3 weeks (31-week gestation) to 13 years presented with large palpable renal swelling (n = 12) and hematuria (n = 3). Computed tomography (CT) scan showed features typical of the tumor. Final histopathology (age group [mean]) showed: multilocular cystic nephroma (MLCN) - n = 5 (41.7%), (11–16 months [13.6]); congenital mesoblastic nephroma (CMN) - n = 4 (33.3%) (classic 1, cellular 3) (0.75–5 months [2.125]); mature cystic teratoma - n = 1 (8.3%): (48 months, in a horseshoe kidney), and angiomyolipoma (AML) - n = 2 (16.7%) (144 months [sporadic] and 156 months [tuberous sclerosis]) One patient with cystic teratoma with no calcification on CT scan received pre-operative chemotherapy as fine-needle aspiration cytology (FNAC) reported malignant small blue cell tumor. Nephroureterectomy with Gerota's fascia could be done easily in all without intraoperative complications. Delay in presentation in MLCN and CMN led to increased symptoms and CT scan changes. All patients did well in 1.5–12 years (median 3 years) follow-up including cellular mesoblastic nephroma. Conclusions: Benign renal tumors often occur in specific age groups but may overlap that of Wilms tumor. Proper interpretation of clinical presentation, CT scan, and FNAC findings help in avoiding preoperative chemotherapy. Upfront nephroureterectomy is curative. Histopathological findings decide further treatment. Children with AML and tuberous sclerosis need lifelong follow-up.
format	article
author	Prema Menon Katragadda Lakshmi Narasimha Rao Saalim Nazki Saswati Behera Kirti Gupta Ram Samujh Shailesh Solanki Akshay Saxena Deepak Bansal Amita Trehan
author_facet	Prema Menon Katragadda Lakshmi Narasimha Rao Saalim Nazki Saswati Behera Kirti Gupta Ram Samujh Shailesh Solanki Akshay Saxena Deepak Bansal Amita Trehan
author_sort	Prema Menon
title	Benign renal tumors in pediatric age group: Retrospective analysis
title_short	Benign renal tumors in pediatric age group: Retrospective analysis
title_full	Benign renal tumors in pediatric age group: Retrospective analysis
title_fullStr	Benign renal tumors in pediatric age group: Retrospective analysis
title_full_unstemmed	Benign renal tumors in pediatric age group: Retrospective analysis
title_sort	benign renal tumors in pediatric age group: retrospective analysis
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/a3a6f0a2117b492187e52bdbc696e602
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Benign renal tumors in pediatric age group: Retrospective analysis

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