From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view

Mafalda Cavalheiro et al. use single-cell force spectroscopy and RNA-seq to examine the adhesion process of Candida glabrata, an opportunistic human fungal pathogen, to various medical surfaces. Their results suggest that the adhesion forces of C. glabrata to medical material are stronger than those...

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Autores principales: Mafalda Cavalheiro, Diana Pereira, Cécile Formosa-Dague, Carolina Leitão, Pedro Pais, Easter Ndlovu, Romeu Viana, Andreia I. Pimenta, Rui Santos, Azusa Takahashi-Nakaguchi, Michiyo Okamoto, Mihaela Ola, Hiroji Chibana, Arsénio M. Fialho, Geraldine Butler, Etienne Dague, Miguel C. Teixeira
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a3c1846e2a0444b58853c7ecafecb7f2
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spelling oai:doaj.org-article:a3c1846e2a0444b58853c7ecafecb7f22021-12-02T16:26:20ZFrom the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view10.1038/s42003-021-02412-72399-3642https://doaj.org/article/a3c1846e2a0444b58853c7ecafecb7f22021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02412-7https://doaj.org/toc/2399-3642Mafalda Cavalheiro et al. use single-cell force spectroscopy and RNA-seq to examine the adhesion process of Candida glabrata, an opportunistic human fungal pathogen, to various medical surfaces. Their results suggest that the adhesion forces of C. glabrata to medical material are stronger than those presented for epithelial cells, and highlight the underlying molecular pathways related to adhesion and biofilm formation in this species.Mafalda CavalheiroDiana PereiraCécile Formosa-DagueCarolina LeitãoPedro PaisEaster NdlovuRomeu VianaAndreia I. PimentaRui SantosAzusa Takahashi-NakaguchiMichiyo OkamotoMihaela OlaHiroji ChibanaArsénio M. FialhoGeraldine ButlerEtienne DagueMiguel C. TeixeiraNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mafalda Cavalheiro
Diana Pereira
Cécile Formosa-Dague
Carolina Leitão
Pedro Pais
Easter Ndlovu
Romeu Viana
Andreia I. Pimenta
Rui Santos
Azusa Takahashi-Nakaguchi
Michiyo Okamoto
Mihaela Ola
Hiroji Chibana
Arsénio M. Fialho
Geraldine Butler
Etienne Dague
Miguel C. Teixeira
From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
description Mafalda Cavalheiro et al. use single-cell force spectroscopy and RNA-seq to examine the adhesion process of Candida glabrata, an opportunistic human fungal pathogen, to various medical surfaces. Their results suggest that the adhesion forces of C. glabrata to medical material are stronger than those presented for epithelial cells, and highlight the underlying molecular pathways related to adhesion and biofilm formation in this species.
format article
author Mafalda Cavalheiro
Diana Pereira
Cécile Formosa-Dague
Carolina Leitão
Pedro Pais
Easter Ndlovu
Romeu Viana
Andreia I. Pimenta
Rui Santos
Azusa Takahashi-Nakaguchi
Michiyo Okamoto
Mihaela Ola
Hiroji Chibana
Arsénio M. Fialho
Geraldine Butler
Etienne Dague
Miguel C. Teixeira
author_facet Mafalda Cavalheiro
Diana Pereira
Cécile Formosa-Dague
Carolina Leitão
Pedro Pais
Easter Ndlovu
Romeu Viana
Andreia I. Pimenta
Rui Santos
Azusa Takahashi-Nakaguchi
Michiyo Okamoto
Mihaela Ola
Hiroji Chibana
Arsénio M. Fialho
Geraldine Butler
Etienne Dague
Miguel C. Teixeira
author_sort Mafalda Cavalheiro
title From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
title_short From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
title_full From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
title_fullStr From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
title_full_unstemmed From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
title_sort from the first touch to biofilm establishment by the human pathogen candida glabrata: a genome-wide to nanoscale view
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a3c1846e2a0444b58853c7ecafecb7f2
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