Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage

Ba Van Vu, Quyet Nguyen et al. investigate the mechanism by which transposable elements are targeted for DNA methylation, using the fungus Pyricularia oryzae as a model system. They find that copy number-dependent DNA methylation and thus silencing of the MAGGY retrotransposon requires cooperative a...

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Autores principales: Ba Van Vu, Quyet Nguyen, Yuki Kondo-Takeoka, Toshiki Murata, Naoki Kadotani, Giang Thi Nguyen, Takayuki Arazoe, Shuichi Ohsato, Hitoshi Nakayashiki
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a3c1a95ef29c43c49d40c14ca484a0eb
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spelling oai:doaj.org-article:a3c1a95ef29c43c49d40c14ca484a0eb2021-12-02T17:05:10ZCopy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage10.1038/s42003-021-01836-52399-3642https://doaj.org/article/a3c1a95ef29c43c49d40c14ca484a0eb2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01836-5https://doaj.org/toc/2399-3642Ba Van Vu, Quyet Nguyen et al. investigate the mechanism by which transposable elements are targeted for DNA methylation, using the fungus Pyricularia oryzae as a model system. They find that copy number-dependent DNA methylation and thus silencing of the MAGGY retrotransposon requires cooperative action of homologous recombination and RNA silencing machinery.Ba Van VuQuyet NguyenYuki Kondo-TakeokaToshiki MurataNaoki KadotaniGiang Thi NguyenTakayuki ArazoeShuichi OhsatoHitoshi NakayashikiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Ba Van Vu
Quyet Nguyen
Yuki Kondo-Takeoka
Toshiki Murata
Naoki Kadotani
Giang Thi Nguyen
Takayuki Arazoe
Shuichi Ohsato
Hitoshi Nakayashiki
Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage
description Ba Van Vu, Quyet Nguyen et al. investigate the mechanism by which transposable elements are targeted for DNA methylation, using the fungus Pyricularia oryzae as a model system. They find that copy number-dependent DNA methylation and thus silencing of the MAGGY retrotransposon requires cooperative action of homologous recombination and RNA silencing machinery.
format article
author Ba Van Vu
Quyet Nguyen
Yuki Kondo-Takeoka
Toshiki Murata
Naoki Kadotani
Giang Thi Nguyen
Takayuki Arazoe
Shuichi Ohsato
Hitoshi Nakayashiki
author_facet Ba Van Vu
Quyet Nguyen
Yuki Kondo-Takeoka
Toshiki Murata
Naoki Kadotani
Giang Thi Nguyen
Takayuki Arazoe
Shuichi Ohsato
Hitoshi Nakayashiki
author_sort Ba Van Vu
title Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage
title_short Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage
title_full Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage
title_fullStr Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage
title_full_unstemmed Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage
title_sort copy number-dependent dna methylation of the pyricularia oryzae maggy retrotransposon is triggered by dna damage
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a3c1a95ef29c43c49d40c14ca484a0eb
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