Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome

The Bacillus haemolytic enterotoxin haemolysin BL has been shown to activate the NLRP3 inflammasome. Here the authors show that a non-haemolytic enterotoxin (NHE) from B. cereus can also activate the NLRP3 inflammasome with a similar mechanism of lytic pore formation.

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Autores principales:	Daniel Fox, Anukriti Mathur, Yansong Xue, Yunqi Liu, Wei Hong Tan, Shouya Feng, Abhimanu Pandey, Chinh Ngo, Jenni A. Hayward, Ines I. Atmosukarto, Jason D. Price, Matthew D. Johnson, Nadja Jessberger, Avril A. B. Robertson, Gaetan Burgio, David C. Tscharke, Edward M. Fox, Denisse L. Leyton, Nadeem O. Kaakoush, Erwin Märtlbauer, Stephen H. Leppla, Si Ming Man
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a3d1c668fd514f4c9ccf1972f0c941e9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:a3d1c668fd514f4c9ccf1972f0c941e92021-12-02T15:39:29ZBacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome10.1038/s41467-020-14534-32041-1723https://doaj.org/article/a3d1c668fd514f4c9ccf1972f0c941e92020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14534-3https://doaj.org/toc/2041-1723The Bacillus haemolytic enterotoxin haemolysin BL has been shown to activate the NLRP3 inflammasome. Here the authors show that a non-haemolytic enterotoxin (NHE) from B. cereus can also activate the NLRP3 inflammasome with a similar mechanism of lytic pore formation.Daniel FoxAnukriti MathurYansong XueYunqi LiuWei Hong TanShouya FengAbhimanu PandeyChinh NgoJenni A. HaywardInes I. AtmosukartoJason D. PriceMatthew D. JohnsonNadja JessbergerAvril A. B. RobertsonGaetan BurgioDavid C. TscharkeEdward M. FoxDenisse L. LeytonNadeem O. KaakoushErwin MärtlbauerStephen H. LepplaSi Ming ManNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniel Fox Anukriti Mathur Yansong Xue Yunqi Liu Wei Hong Tan Shouya Feng Abhimanu Pandey Chinh Ngo Jenni A. Hayward Ines I. Atmosukarto Jason D. Price Matthew D. Johnson Nadja Jessberger Avril A. B. Robertson Gaetan Burgio David C. Tscharke Edward M. Fox Denisse L. Leyton Nadeem O. Kaakoush Erwin Märtlbauer Stephen H. Leppla Si Ming Man Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
description	The Bacillus haemolytic enterotoxin haemolysin BL has been shown to activate the NLRP3 inflammasome. Here the authors show that a non-haemolytic enterotoxin (NHE) from B. cereus can also activate the NLRP3 inflammasome with a similar mechanism of lytic pore formation.
format	article
author	Daniel Fox Anukriti Mathur Yansong Xue Yunqi Liu Wei Hong Tan Shouya Feng Abhimanu Pandey Chinh Ngo Jenni A. Hayward Ines I. Atmosukarto Jason D. Price Matthew D. Johnson Nadja Jessberger Avril A. B. Robertson Gaetan Burgio David C. Tscharke Edward M. Fox Denisse L. Leyton Nadeem O. Kaakoush Erwin Märtlbauer Stephen H. Leppla Si Ming Man
author_facet	Daniel Fox Anukriti Mathur Yansong Xue Yunqi Liu Wei Hong Tan Shouya Feng Abhimanu Pandey Chinh Ngo Jenni A. Hayward Ines I. Atmosukarto Jason D. Price Matthew D. Johnson Nadja Jessberger Avril A. B. Robertson Gaetan Burgio David C. Tscharke Edward M. Fox Denisse L. Leyton Nadeem O. Kaakoush Erwin Märtlbauer Stephen H. Leppla Si Ming Man
author_sort	Daniel Fox
title	Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
title_short	Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
title_full	Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
title_fullStr	Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
title_full_unstemmed	Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
title_sort	bacillus cereus non-haemolytic enterotoxin activates the nlrp3 inflammasome
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a3d1c668fd514f4c9ccf1972f0c941e9
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Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome

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