Comparative assessment of prevalence of fibrinogen (-455)G>A gene polymorphism in teenagers from various populations of Eastern Siberia

This study was performed to establish prevalence of alleles of polymorphism (-455)G>A of в-chain of fibrinogen gene in Russian and Buryat populations of Eastern Siberia. We used blood database of children and teenagers of Russian and Buryat nationality. Genotyping was carried out by a standard PC...

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Main Authors: A. Y. Senkina, T. A. Bairova, S. I. Kolesnikov, O. V. Kalyuzhnaya
Format: article
Language:RU
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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Online Access:https://doaj.org/article/a3d459a38a8c4ac18f7e1700432cdd6a
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Summary:This study was performed to establish prevalence of alleles of polymorphism (-455)G>A of в-chain of fibrinogen gene in Russian and Buryat populations of Eastern Siberia. We used blood database of children and teenagers of Russian and Buryat nationality. Genotyping was carried out by a standard PCR method. Frequency of allele A in Russian population was 28,0 %, in Buryat population - 23,7 %. There were no statistically significant ethnic differences between these samples.