Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana

Abstract Beauveria bassiana is a species complex whose isolates show considerable natural genetic variability. However, little is known about how this genetic diversity affects the fungus performance. Herein, we characterized the diversity of genes involved in various mechanisms of the infective cyc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Laila Gasmi, Sehyeon Baek, Jong Cheol Kim, Sihyeon Kim, Mi Rong Lee, So Eun Park, Tae Young Shin, Se Jin Lee, Bruce L. Parker, Jae Su Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a3d4de234d1d47df91e408dfe3d97551
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a3d4de234d1d47df91e408dfe3d97551
record_format	dspace
spelling	oai:doaj.org-article:a3d4de234d1d47df91e408dfe3d975512021-12-02T15:14:14ZGene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana10.1038/s41598-020-78910-12045-2322https://doaj.org/article/a3d4de234d1d47df91e408dfe3d975512021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78910-1https://doaj.org/toc/2045-2322Abstract Beauveria bassiana is a species complex whose isolates show considerable natural genetic variability. However, little is known about how this genetic diversity affects the fungus performance. Herein, we characterized the diversity of genes involved in various mechanisms of the infective cycle of 42 isolates that have different growth rates, thermotolerance and virulence. The analysed genes showed general genetic diversity measured as non-synonymous changes (NSC) and copy number variation (CNV), with most of them being subjected to positive episodic diversifying selection. Correlation analyses between NSC or CNV and the isolate virulence, thermotolerance and growth rate revealed that various genes shaped the biological features of the fungus. Lectin-like, mucin signalling, Biotrophy associated and chitinase genes NSCs correlated with the three biological features of B. bassiana. In addition, other genes (i.e. DNA photolyase and cyclophilin B) that had relatively conserved sequences, had variable CNs across the isolates which were correlated with the variability of either virulence or thermotolerance of B. bassiana isolates. The data obtained is important for a better understanding of population structure, ecological and potential impact when isolates are used as mycoinsecticides and can justify industrialization of new isolates.Laila GasmiSehyeon BaekJong Cheol KimSihyeon KimMi Rong LeeSo Eun ParkTae Young ShinSe Jin LeeBruce L. ParkerJae Su KimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Laila Gasmi Sehyeon Baek Jong Cheol Kim Sihyeon Kim Mi Rong Lee So Eun Park Tae Young Shin Se Jin Lee Bruce L. Parker Jae Su Kim Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana
description	Abstract Beauveria bassiana is a species complex whose isolates show considerable natural genetic variability. However, little is known about how this genetic diversity affects the fungus performance. Herein, we characterized the diversity of genes involved in various mechanisms of the infective cycle of 42 isolates that have different growth rates, thermotolerance and virulence. The analysed genes showed general genetic diversity measured as non-synonymous changes (NSC) and copy number variation (CNV), with most of them being subjected to positive episodic diversifying selection. Correlation analyses between NSC or CNV and the isolate virulence, thermotolerance and growth rate revealed that various genes shaped the biological features of the fungus. Lectin-like, mucin signalling, Biotrophy associated and chitinase genes NSCs correlated with the three biological features of B. bassiana. In addition, other genes (i.e. DNA photolyase and cyclophilin B) that had relatively conserved sequences, had variable CNs across the isolates which were correlated with the variability of either virulence or thermotolerance of B. bassiana isolates. The data obtained is important for a better understanding of population structure, ecological and potential impact when isolates are used as mycoinsecticides and can justify industrialization of new isolates.
format	article
author	Laila Gasmi Sehyeon Baek Jong Cheol Kim Sihyeon Kim Mi Rong Lee So Eun Park Tae Young Shin Se Jin Lee Bruce L. Parker Jae Su Kim
author_facet	Laila Gasmi Sehyeon Baek Jong Cheol Kim Sihyeon Kim Mi Rong Lee So Eun Park Tae Young Shin Se Jin Lee Bruce L. Parker Jae Su Kim
author_sort	Laila Gasmi
title	Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana
title_short	Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana
title_full	Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana
title_fullStr	Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana
title_full_unstemmed	Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana
title_sort	gene diversity explains variation in biological features of insect killing fungus, beauveria bassiana
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a3d4de234d1d47df91e408dfe3d97551
work_keys_str_mv	AT lailagasmi genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT sehyeonbaek genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT jongcheolkim genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT sihyeonkim genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT mironglee genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT soeunpark genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT taeyoungshin genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT sejinlee genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT brucelparker genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana AT jaesukim genediversityexplainsvariationinbiologicalfeaturesofinsectkillingfungusbeauveriabassiana
_version_	1718387589910626304

Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana

Ejemplares similares