Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.

<h4>Background</h4>Children born preterm, particularly at earlier gestations, are at increased risk for mortality and morbidity, but later health-related quality of life (HRQoL) is less well described. Neurodevelopmental impairment and socio-economic status may also influence HRQoL. Our...

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Autores principales:	Gordon X H Liu, Jane E Harding, PIANO Study Team
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a3db205694f840cfb1e83bc3f8124925
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spelling	oai:doaj.org-article:a3db205694f840cfb1e83bc3f81249252021-12-02T20:10:58ZCaregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.1932-620310.1371/journal.pone.0253026https://doaj.org/article/a3db205694f840cfb1e83bc3f81249252021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253026https://doaj.org/toc/1932-6203<h4>Background</h4>Children born preterm, particularly at earlier gestations, are at increased risk for mortality and morbidity, but later health-related quality of life (HRQoL) is less well described. Neurodevelopmental impairment and socio-economic status may also influence HRQoL. Our aim was to describe the HRQoL of a cohort of New Zealand children born very and extremely preterm, and how this is related to neurodevelopmental impairment, gestational age, and socio-economic deprivation.<h4>Methods</h4>Children born <30 weeks' gestation or <1500 g birthweight were assessed at 7 years' corrected age. Caregivers completed the Child Health Questionnaire Parent Form (CHQ-PF50), and the Health Utilities Index Mark 2 (HUI-2). Neurodevelopmental impairment was defined as Wechsler full scale intelligence quotient below -1 standard deviation (SD), Movement Assessment Battery for Children total score ≤15 percentile, cerebral palsy, deafness, or blindness.<h4>Results</h4>Data were collected for 127 children, of whom 60 (47%) had neurodevelopmental impairment. Overall, HRQoL was good: mean (SD) CHQ-PF50 physical summary score = 50.8 (11.1), psychosocial summary score = 49.3 (9.1) [normative mean 50 (10)]; HUI-2 dead-healthy scale = 0.92 (0.09) [maximum 1.0]. Neurodevelopmental impairment, lower gestational age, and higher socio-economic deprivation were all associated with reduced HRQoL. However, on multivariable analysis, only intelligence quotient and motor function were associated with psychosocial HRQoL, while intelligence quotient was associated with physical HRQoL.<h4>Conclusions</h4>Most seven-year-old children born very and extremely preterm have good HRQoL. Further improvements will require reduced neurodevelopmental impairment.Gordon X H LiuJane E HardingPIANO Study TeamPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253026 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Gordon X H Liu Jane E Harding PIANO Study Team Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.
description	<h4>Background</h4>Children born preterm, particularly at earlier gestations, are at increased risk for mortality and morbidity, but later health-related quality of life (HRQoL) is less well described. Neurodevelopmental impairment and socio-economic status may also influence HRQoL. Our aim was to describe the HRQoL of a cohort of New Zealand children born very and extremely preterm, and how this is related to neurodevelopmental impairment, gestational age, and socio-economic deprivation.<h4>Methods</h4>Children born <30 weeks' gestation or <1500 g birthweight were assessed at 7 years' corrected age. Caregivers completed the Child Health Questionnaire Parent Form (CHQ-PF50), and the Health Utilities Index Mark 2 (HUI-2). Neurodevelopmental impairment was defined as Wechsler full scale intelligence quotient below -1 standard deviation (SD), Movement Assessment Battery for Children total score ≤15 percentile, cerebral palsy, deafness, or blindness.<h4>Results</h4>Data were collected for 127 children, of whom 60 (47%) had neurodevelopmental impairment. Overall, HRQoL was good: mean (SD) CHQ-PF50 physical summary score = 50.8 (11.1), psychosocial summary score = 49.3 (9.1) [normative mean 50 (10)]; HUI-2 dead-healthy scale = 0.92 (0.09) [maximum 1.0]. Neurodevelopmental impairment, lower gestational age, and higher socio-economic deprivation were all associated with reduced HRQoL. However, on multivariable analysis, only intelligence quotient and motor function were associated with psychosocial HRQoL, while intelligence quotient was associated with physical HRQoL.<h4>Conclusions</h4>Most seven-year-old children born very and extremely preterm have good HRQoL. Further improvements will require reduced neurodevelopmental impairment.
format	article
author	Gordon X H Liu Jane E Harding PIANO Study Team
author_facet	Gordon X H Liu Jane E Harding PIANO Study Team
author_sort	Gordon X H Liu
title	Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.
title_short	Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.
title_full	Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.
title_fullStr	Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.
title_full_unstemmed	Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.
title_sort	caregiver-reported health-related quality of life of new zealand children born very and extremely preterm.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/a3db205694f840cfb1e83bc3f8124925
work_keys_str_mv	AT gordonxhliu caregiverreportedhealthrelatedqualityoflifeofnewzealandchildrenbornveryandextremelypreterm AT janeeharding caregiverreportedhealthrelatedqualityoflifeofnewzealandchildrenbornveryandextremelypreterm AT pianostudyteam caregiverreportedhealthrelatedqualityoflifeofnewzealandchildrenbornveryandextremelypreterm
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Caregiver-reported health-related quality of life of New Zealand children born very and extremely preterm.

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