Novel IL-12Rβ1 deficiency-mediates recurrent cutaneous leishmaniasis

Novel IL-12Rβ1 deficiency-mediates recurrent cutaneous leishmaniasis

Background: The IL-12/IFN-γ axis plays a vital role in the control of intramacrophagic pathogens including Leishmania infections.Objective: The aim of this study was to investigate genetic defects in the IL-12/IFN-γ axis in cutaneous leishmaniasis patients, using immunological and genetic evaluation...

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Autores principales: Farhad Ali Khattak, Noor ul Akbar, Maira Riaz, Mubashir Hussain, Khalid Rehman, Shahid Niaz Khan, Taj Ali Khan
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
IL-12Rβ1
IL-12/IFN-γ axis
cutaneous leishmaniasis
deficiency
recurrent infection
Infectious and parasitic diseases
RC109-216
Acceso en línea:https://doaj.org/article/a3e0a25a0a6c4067913ffb154265f871
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https://doaj.org/article/a3e0a25a0a6c4067913ffb154265f871

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