Novel IL-12Rβ1 deficiency-mediates recurrent cutaneous leishmaniasis

Background: The IL-12/IFN-γ axis plays a vital role in the control of intramacrophagic pathogens including Leishmania infections.Objective: The aim of this study was to investigate genetic defects in the IL-12/IFN-γ axis in cutaneous leishmaniasis patients, using immunological and genetic evaluation...

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Autores principales:	Farhad Ali Khattak, Noor ul Akbar, Maira Riaz, Mubashir Hussain, Khalid Rehman, Shahid Niaz Khan, Taj Ali Khan
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	IL-12Rβ1 IL-12/IFN-γ axis cutaneous leishmaniasis deficiency recurrent infection Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/a3e0a25a0a6c4067913ffb154265f871
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Novel IL-12Rβ1 deficiency-mediates recurrent cutaneous leishmaniasis

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